Examples of 'immunodominant' in a sentence
Meaning of "immunodominant"
Immunodominant is an adjective used in immunology to describe a specific antigen or epitope that elicits a strong immune response
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- Relating to the epitope of a molecule that provokes the most intense immune response
How to use "immunodominant" in a sentence
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immunodominant
Immunodominant determinant regions are likely to be good tolerogens.
Boxes around bars indicate immunodominant peptides.
This immunodominant region clearly contains conformational type epitopes and linear type epitopes.
The constructs may include immunodominant epitopes of HBsAg.
Preferably the antigen induces the production of neutralising antibodies against the immunodominant repeat.
Serum raised against a recombinant immunodominant antigen of capripoxvirus has been.
The range of the decrease can also vary if the epitope is an immunodominant epitope.
We foresee the use of dampened immunodominant epitopes as a novel vaccine strategy.
These experimental results show that these peptides are immunodominant peptides.
Boxes around bars indicate the immunodominant peptides that were previously used.
Such a selection should also avoid epitopes that may act as immunodominant decoys.
The proteolytic kinetics of these immunodominant peptides were analyzed at the small intestinal surface.
These epitopes are termed immunodominant.
The left panel shows the immunodominant response to an epitope derived from influenza matrix protein.
An antigen can have one or more immunodominant epitopes.
See also
It is an immunodominant conserved antigen ;.
This method can also be used to identify immunodominant proteins.
Unprotective antigens or immunodominant but variable proteins or detrimental e . g.
Brush border membrane catalyzed digestion of the immunodominant gliadin peptide.
Although clone 98 represented the immunodominant epitope some clones seemed to possess a higher IgE binding capacity.
The peptides used in the present invention may comprise one or several immunodominant epitopes.
Lmmunodominant antigens and the respective immunodominant epitopes are well known for each of these pathogens.
Even more preferably, said antigenic fragment comprises an immunodominant epitope.
Monoclonal antibodies to immunodominant epitope of Tropheryma whipplei.
Such treatment may be employed only if cancer / testis antigens remain immunodominant.
Trimeric viral cell entry proteins are the immunodominant surface antigens of many viruses.
Furthermore, two pairs of monoclonal antibodies recognize two epitopes that are possibly immunodominant.
EAE is induced in susceptible animals by immunodominant epitopes of the myelin sheath.
This can be accomplished through site-directed mutagenesis of the gene encoding the immunodominant epitope.
These internal proteins contain highly conserved and immunodominant regions making them ideal T cell targets.
The six immunodominant sequences used in Example 1 are bolded.
Another object of the invention is to identify immunodominant regions of HCV core protein.
Other suitable immunodominant T-cell epitopes may be used at a later stage.
This approach may be utilized to map major immunodominant epitopes for CTL induction.
An immunodominant region has been thus determined in the C-terminal region of the mature FHA.
This region of guinea pig MBP therefore corresponds to the immunodominant epitope of the protein.
The immunodominant T-cell antigen in this complex mixture has been identified in three different models.
Glycoprotein D is also an immunodominant protein.
An ENO immunodominant peptide was identified and referred as to EP 1.
However, known peptides may represent immunodominant peptides.
The remaining immunodominant epitopes are typically referred to as " secondary " immunodominant epitope ( s ).
However, this region is not normally an immunodominant epitope on the glycoprotein.
All tested patients displayed IgE-reactivity with clone 98 which therefore contained an immunodominant epitope.
This method may also be used to identify immunodominant antigens and / or epitopes within antigens.
Based on this study, several discontinuous epitopes are located within this immunodominant region.
Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants.
The vertical axis shows the % response in the 3 subjects in relation to the immunodominant epitope.
Many of these analogues also maintain an immunodominant S1 epitope recognized by a protective monoclonal antibody.
In one embodiment of the invention, a DIVA antigen comprises an immunodominant epitope or region.
Such antibodies specific for this immunodominant region is used for clinical diagnosis of HIV-1 infection.
