Examples of 'immunomodulatory compound' in a sentence
Meaning of "immunomodulatory compound"
immunomodulatory compound: Substance that can alter or regulate the immune response
How to use "immunomodulatory compound" in a sentence
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immunomodulatory compound
An immunomodulatory compound is then administered directly to the patient.
The invention generally relates to methods of determining the efficacy of an immunomodulatory compound.
The combined use of the immunomodulatory compound and transplantation therapy provides a unique and unexpected synergism.
The specification also discloses that said compound is a small immunomodulatory compound of the invention.
Administration of an immunomodulatory compound of the formula I can upregulate an immune response in a subject.
FIELD Provided herein are methods of determining the efficacy of an immunomodulatory compound.
In a specific embodiment, said immunomodulatory compound is lenalidomide or pomalidomide.
In another aspect, said composition comprises an immunomodulatory compound.
In specific embodiments, said immunomodulatory compound is lenalidomide or pomalidomide.
In another specific embodiment, said composition comprises an immunomodulatory compound.
In another example, the immunomodulatory compound is pomalidomide, or lenalidomide.
In another specific embodiment, said composition additionally comprises an immunomodulatory compound or thalidomide.
In certain embodiments, the immunomodulatory compound is an amino-substituted isoindoline.
In another aspect of the disclosure, said composition additionally comprises an immunomodulatory compound or thalidomide.
In certain examples, the immunomodulatory compound is an amino-substituted isoindoline.
See also
In an advantageous embodiment, a kit of the disclosure contains leflunomide and no additional immunomodulatory compound.
In another preferred embodiment, the immunomodulatory compound is pomalidomide, or lenalidomide.
The immunomodulatory compound of the invention enhances the degradation of TNF-a mRNA.
In another more specific embodiment, said immunomodulatory compound is lenalidomide or pomalidomide.
In other words, the invention encompasses the use of the R or S enantiomer of immunomodulatory compound.
In one aspect of the disclosure, said immunomodulatory compound is lenalidomide or pomalidomide.
The immunomodulatory compound of Formula I enhances the degradation of TNF-a mRNA.
In another aspect of the disclosure, said immunomodulatory compound is lenalidomide or pomalidomide.
The immunomodulatory compound can be any compound described below, e.g., lenalidomide or pomalidomide.
Pharmaceutical compositions, dosing regimen, and combination therapies using an immunomodulatory compound are also described.
In a preferred embodiment, the immunomodulatory compound is used alone, that is without other chemotherapeutics.
According to one embodiment of the invention, the immunomodulatory compound is of formula I,.
In another embodiment, the immunomodulatory compound provided herein provided herein binds directly to CRBN-DDB1.
TSNK cells, not contacted with said immunomodulatory compound or thalidomide.
An immunomodulatory compound described in Section 5.9, below, or thalidomide.
An immunomodulatory compound described in Section 6.2.1 below, or thalidomide, prior to said administration.
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The mechanism of these immunomodulatory activities is unknown
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I have the same compound on the bike
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