Examples of 'immunotoxins' in a sentence
Meaning of "immunotoxins"
Immunotoxins (noun) - a type of protein that combines an antibody and a toxin, used in targeted therapy to destroy cancer cells
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- plural of immunotoxin
How to use "immunotoxins" in a sentence
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immunotoxins
Administrations of the immunotoxins according to standard techniques.
Immunotoxins are administered vía a central venous catheter.
Compositions comprising immunoconjugates or immunotoxins are also provided.
Also immunotoxins based on immunoglobulin fragments have been described.
Maybe he could get the immunotoxins on the side.
Immunotoxins with these mutations are expected to be less immunogenic.
He could get immunotoxins on the side.
Complexes of toxin and antibody have been termed immunotoxins.
Single chain immunotoxins may be used.
Antibodies can be modified to act as immunotoxins.
A new application of immunotoxins has been discovered.
Such molecules are often referred to immunotoxins.
Methods for producing immunotoxins of antibodies are well known.
A variety of cytotoxic agents are suitable for use in immunotoxins.
The described immunotoxins can be used in the invention.
See also
A logical consequence of these problems is the development of human immunotoxins.
Each of these immunotoxins is or has been the subject of a clinical trial.
Also described herein are immunotoxins.
Immunotoxins are an example of such conjugates.
This immunogenicity of recombinant immunotoxins reduces their therapeutic usefulness.
Immunotoxins were originally composed of an antibody chemically conjugated to a plant or a bacterial toxin.
This approach has been for example adopted in the case of immunotoxins.
Both immunotoxins were prepared and tested on two mesothelin expressing cell lines.
Immunotoxin research has focused on developing immunotoxins for cancer therapy.
The two immunotoxins had comparable activity against several cell lines.
Active immunization has not been used as often as passive immunotherapy or immunotoxins.
Immunotoxins can typically be administered multiple times to patients with hematological malignancies.
The antibodies can be used in a corresponding way to obtain such immunotoxins.
Production of these immunotoxins may be achieved in either procaryotic or eucaryotic expression systems.
Other potential risk factors include mechanical trauma and exposure to immunotoxins.
The immunotoxins of the present invention may also be used in an in vitro method.
Toxins can be employed with antibodies of the present invention to yield immunotoxins.
Such immunotoxins can be used to purge a blood sample or culture of lymphocytes from a patient.
The subject polypeptides can be used to make fusión proteins such as immunotoxins.
Recombinant immunotoxins selectively kill cells which are recognized by the antigen binding domain.
One factor that contributes to the therapeutic usefulness of immunotoxins is their stability.
Conjugates that are immunotoxins including conventional antibodies have been widely described in the art.
Several catalytic domains of bacterial toxins have been used for constructing immunotoxins.
Each of immunotoxins and radiolabeled molecules would be likely to kill cells expressing TNFa.
These results have important clinical implications for the use of immunotoxins in patients.
This invention relates generally to immunotoxins and more particularly to immunotoxin therapy of allergy.
Toxins can be employed with the monoclonal antibodies described herein to produce immunotoxins.
Other vaccines and immunotoxins are also well known to those skilled in the art.
Cell viability assay of HUVEC cells contacted with various immunotoxins.
Treatment of solid tumors with immunotoxins can be improved by the following novel method.
Immunotoxins may also be designed which target cytotoxic agents to specific sites in the body.
Generation of the IgG antibodies to the immunotoxins in mice is illustrated in FIG.
This gives modified immunotoxins which have acquired a new character as regards their pharmacokinetic properties.
RNases can be fused with specific membranal protein antibodies to create immunotoxins.
These immunotoxins are minimally immunogenic and generate less systemic toxicity than presently known immunotoxins.
