Examples of 'important mediators' in a sentence

Meaning of "important mediators"

important mediators: significant elements or individuals that play a crucial role in a particular situation

How to use "important mediators" in a sentence

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important mediators
Cytokines are thought to be important mediators in this response.
This enables one to develop more selective drugs to control pathophysiologically important mediators.
Unions can become important mediators between institutes and employees.
VEGF and the genes in the VEGF pathway are considered important mediators of cancer progression.
They are also important mediators in terms of processes such as allergy or asthma.
Protein-carbohydrate interactions are now recognized to be important mediators of cell communication.
Leukotrienes can also be important mediators of inflammation in inflammatory bowel disease.
Protein kinase-associated activities are moderated by chemokines, which are important mediators of inflammation.
Prostaglandins are important mediators of inflammation that are produced at elevated levels in inflamed tissues.
In this manner, other genetic targets can be defined as important mediators of the disease.
Innate cells are also important mediators in the activation of the adaptive immune system.
There is, therefore, good evidence that the leukotrienes are important mediators of human asthma.
Its important mediators bradykinin and kallidin are vasodilators and act on many cell types.
Several studies point to cytokines as important mediators associated with the pathogenesis of periodontitis.
The products of these enzymes, prostaglandins and NO, are important mediators of pain and inflammation.

See also

TNF-a, which are important mediators of endotoxin-induced shock, aggravating the effects of endotoxin in vivo.
CTL have long been known to be important mediators of viral immunity.
I am counting on you as important mediators taking the message out into the Member States.
PGE2 contributes to increased expression of matrix metalloproteinases that are important mediators of cartilage degradation.
In the CNS, NMDA receptors are important mediators of glutamate-mediated neurotransmission and synaptic plasticity.
Natural killer ( NK ) cells are Kown to be important mediators of ADCC.
Prostaglandins and related eicosanoids are important mediators and regulators of both immune and inflammatory responses.
Natural killer ( NK ) cells are known to be important mediators of ADCC.
These lymphokines are important mediators of T cell effects.
Abstract, The receptors tyrosine kinase ( RTKs ) CSF-1R and KIT are important mediators of signal transduction.
Socio-economic factors are also important mediators of the environment-health link.
Prostanoids are therefore bioregulators, but they are also important mediators of inflammation and other diseases.
Some cytokines are signaling glycoproteins that are important mediators of synovial inflammation and cartilage destruction.
Inflammation and tumor stroma are important mediators in PDAC progression.
The signature also points to chemokines as important mediators of TGF-β's effects on tumor growth.
Prostanoids are thus bioregulators, but also important mediators of inflammation and of other pathologies.
On the counterpart, NK cells were important mediators of the therapeutic effect.
These findings suggest that endothelin is one of important mediators for endotoxin-induced diseases Biochem.

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