Examples of 'in-frame' in a sentence
Meaning of "in-frame"
in-frame (noun) - In the context of genetics and molecular biology, this term refers to the reading frame in a DNA sequence where the codons are correctly read during translation to produce a protein. A mutation that shifts the reading frame can lead to a non-functional or altered protein. Researchers analyze DNA sequences to identify the in-frame regions that code for proteins
How to use "in-frame" in a sentence
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in-frame
One deletion removed five codons in-frame.
In-frame deletions or duplications have been identified in a few cases.
Asterisks indicate the in-frame stop codons.
The resulting in-frame transcripts should restore dystrophin synthesis.
Oligonucleotide primers were designed to make a series of precise in-frame deletions.
There were no in-frame stop codons upstream of the initiator methionine.
The following figures have been directly portrayed in-frame in the strip.
In-frame mutations may slightly alter the functionality of the protein.
The primers were selected to produce an in-frame deletion in the scpA gene.
In-frame fusion transcripts can generate functional domains from both fusion partners.
Beginning with a start codon and preceded by an in-frame stop codon.
Two initiation sites are in-frame if they are in the same triplet reading frame.
This minor improvement allows for the formation of in-frame fusion protein.
This was due to the in-frame fusión of the five additional amino acids.
Hatched boxes indicate the relative position of internal in-frame deletion mutations.
See also
To disrupt mxnK by in-frame deletion, a gene inactivation plasmid harbouring two fragments was constructed.
This places the small subunit in-frame with the large subunit.
Sequence analysis revealed a potential open reading frame, preceded by an in-frame stop codon.
The sequence contains an in-frame stop codon upstream of the putative initiating methionine.
The one or more inserted stop codons are preferably in-frame stop codons.
The polyepitope sequences were inserted in-frame within the amino terminal portion of the core gene.
However it is generally preferred to use recombinant manipulations to make the in-frame fusión protein.
The deletions generated in-frame stop codons that truncated PKS polypeptides.
All cloned constructs were performed in our lab and sequenced for correct in-frame orientation.
The first ATG triplet and in-frame stop codon are underlined.
Selenoprotein synthesis requires co-translational recoding of in-frame UGA codons.
Each of the C primers introduces an in-frame initiation codon in the resulting amplification product.
The MKK4 protein sequence presented starts at the second in-frame initiation codon.
Upstream of the ATG is an in-frame terminator providing support for the initiator methionine.
The resulting DNA molecules encode an in-frame fusión protein.
In-frame deletions typically result in Becker because there is some dystrophin present in the cells.
Each of these unique restriction sites results in an in-frame blunt ended digestion product.
All the cameras were synced so animators could then triangulate Crudup 's performance in-frame.
Convenient restriction sites have been included for in-frame fusión of single-chain antibody genes.
The first in-frame ATG codon after the CMV promoter is bolded and italicized.
These variants would encode proteins with in-frame deletions in the N-terminus of the protein.
The ORF contained all the sequenced peptides, but was not preceded by in-frame stop codons.
The resultant DNA sequences were analyzed for in-frame rearrangements and other antibody characteristics.
For in-frame deletions, a selective marker cassette is preferentially used.
Many vectors are commercially available that facilitate sub-cloning WUP in-frame to a fusión moiety.
DNA sequencing confirmed the in-frame orientation of the GILT insertion.
An in-frame stop codon was present 7 nucleotides downstream of the deletion.
The gene F mutation employed in these constructions is the in-frame deletion within this gene.
PCR oligonucleotides for the in-frame linkage of Humicola lipase and the C-terminus of a agglutinin.
The retained intron 5 sequence contains an in-frame stop codon.
These mutations are called in-frame insertions and deletions, respectively.
At least a portion of exon 14 is deleted as a result of said in-frame splicing.
It is fused in-frame to the reporter lacZ gene, linked to a polyA signal.
Upstream of the putative initiating ATG are two in-frame stop codons and no additional ATG 's.
An in-frame termination codon occurs 18 triplets past the junction site.
