Examples of 'increased binding' in a sentence
Meaning of "increased binding"
increased binding: This phrase refers to the action of making something firmer, stronger, or more secure by tightening or fastening it. It could imply a physical tightening of objects or a metaphorical enhancement of a bond or relationship to ensure greater cohesion or reliability
How to use "increased binding" in a sentence
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increased binding
Several mutations resulted in increased binding affinity.
This allows increased binding sites for hydrophobic interactions.
Decreased reaction product indicates increased binding inhibitory activity.
Increased binding avidities are often manifested in slower dissociation rates.
Amino acid substitutions resulting in increased binding affinity were also identified.
Increased binding to FcYRIIB.
This library yielded several variants displaying increased binding affinity.
The araC repressor has increased binding affinity in the presence of arabinose.
These results also demonstrated amino acid substitutions that increased binding affinity.
Such modifications may produce increased binding affinity or improved pharmacokinetic behavior.
Flow rate for rat antibody purification has to be kept low for increased binding efficiency.
The variant polypeptides exhibit increased binding to FcRn as compared to a parent polypeptide.
An increased binding potential means that more labeled receptor can bind within the test zone.
The process of generating antibodies with increased binding affinities is called affinity maturation.
An increased binding affinity is correlated with a lower Kd.
See also
The enhanced activity may be increased binding affinity for the target receptor.
Myeloproliferative neoplasms associated with increased platelet production that cause increased binding of VWF to platelets.
Such modifications can produce increased binding affinity or improved pharmacokinetic behavior.
Only one of the four sets of conditions ( low salt with IgG ) shows increased binding.
Substitutions that result in increased binding as well as decreased binding can be useful.
Increased binding to FcYRIIB as compared to a wild-type Fc domain.
Residue substitutions which lead to increased binding affinity of the peptides can then be identified.
An increased binding was again found 5 minutes after stimulation by the B2AR agonist.
Such multivalent forms can be used to achieve increased binding affinity for the target.
Exhibits increased binding affinity for an FcYRIII ;.
In one embodiment the increased effector function is increased binding to an activating Fc receptor.
Preferably the increased binding affinity is an increased binding affinity to heparan sulphate and / or heparin.
Type II double truncated tau molecules show increased binding affinity to the microtubular system.
Increased binding to serum albumin and / or platelet integrin aIIb 3.
A number of clones were isolated with increased binding affinity as judge from ELISA experiments.
Increased binding to serum albumin and / or platelet integrin aIIbB3.
As before, a positive result was indicated by an increased binding of the label.
Martin does not demonstrate increased binding affinity to FcRn for any of these proposed mutations.
The polypeptide of claim 18 which displays increased binding to an FcYRII.
Figure 4 is a diagram showing increased binding of zearalenone by enzymatically treated yeast cell supernatants.
Supernatant containing anti-HBs gave an increased binding of the label.
Increased binding to an activating FcYR as compared to a wild-type Fc domain ;.
In some aspects, the antibody has increased binding to a FcY receptor.
This apparent increased binding of TIMP-1-GPI was also demonstrated with membrane-type MMPs.
The range of reactivity varies with the pH ; increased binding occurs with increasing pH.
B + = Increased binding of activation dependent ligand ( PAC 1 antibody ) in response to agonist.
Alternatively, the modification may result in an increased binding to mannose and a high clearance rate.
C + = Increased binding of occupancy dependent antibody ( anti-LIBS 1 ) in the presence of activation-independent ligand GRGDSP.
In one aspect, the resulting analog / mimetic exhibits increased binding affinity for myostatin.
The analoged peptide is evaluated for increased binding affinity binding half life and / or increased cross-reactivity.
The polypeptide of claim 27 which displays increased binding to FcRn.
In one embodiment, the increased binding affinity is to an Fc activating receptor.
The polypeptide of claim 18 which displays increased binding to an FcyRIII.
In one embodiment, the increased binding affinity is to an Fc activating reecptor.
Relative FcRn affinity numbers greater than 1.0 demonstrate increased binding over wild type.
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