Examples of 'indolyl' in a sentence
Meaning of "indolyl"
Indolyl refers to a chemical compound containing an indole ring structure, commonly found in various biological molecules like tryptophan
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- An indole radical
How to use "indolyl" in a sentence
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indolyl
Indolyl group is preferred as the heteroaromatic group.
Preferred substrates for hydrolases are indolyl derivatives.
Ar is indolyl or substituted indolyl or a pharmaceutically acceptable salt thereof.
Preferred aryl groups are pyridyl and indolyl.
Is an indolyl group which is unsubstituted or substituted.
Preferred heteroaryl groups include benzimidazolyl and indolyl.
Trp with its indolyl nitrogen substituted with methyl.
An example of a bicyclic substituent is indolyl.
A preferred bicyclic heteroaryl group is indolyl substituted with alkoxycarbonyl groups.
A preferred bicyclic substituent is indolyl.
The indolyl nitrogen of the indenoindolyl group has a substituent containing a basic atom.
Particularly preferred is indolyl.
The indolyl group may be linked to the purine core vÃa any available ring position.
Thus for example the cyclic amine may be an indolyl or isoindolyl group.
A compound according to claim 1, wherein aryl is phenyl and heteroaryl is isoquinolyl or indolyl.
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In such embodiments Ar is preferably optionally substituted indolyl or optionally substituted indazolyl.
The pyrrolyl ring taken together with the phenyl ring forms an indolyl.
Especially ring C is indolyl or quinolinyl.
Particularly preferred Ar groups include pyridyl or indolyl.
In a similar manner the following indolyl derivatives were prepared,.
The preferred meaning for R is indolyl.
Typically the substituent on the indolyl group is an electron-withdrawing group.
Examples include pyridyl, quinolyl and indolyl.
When substituted, the indolyl may be substituted at one or more available ring positions.
More preferably the fused bicyclic heteroaryl group is an indolyl or isoindolyl group.
Indolyl group ( for instance vÃa tryptophan ).
Some of the disclosed compounds contain a quinolone fragment bonded to the indolyl or benzimidazolyl group.
Preferably, R5 is an indolyl represented by the following structural formula, wherein,.
Examples of such groups include benzofuranyl, benzothienyl or indolyl.
In such embodiments Ar may be optionally substituted indolyl and R1 may be optionally substituted phenyl.
In one embodiment, bicyclic heteroaryl is indolyl.
R2 is selected from hydrogen, an indolyl group, and a phenyl group.
In a further embodiment, bicyclic heteroaryl is indolyl.
Bicyclic heteroaryl include benzofuranyl, benzothiophenyl, indolyl and indazolyl, quinolyl and isoquinolyl ( all possible isomers ).
Represents a phenyl group, a pyridyl group or an indolyl group.
A compound as claimed in claim 7, wherein the indolyl group is N-substituted with a methyl substituent.
Examples of bicyclic heterocyclic aromatic rings include eg . quinolinyl or indolyl.
In certain embodiments of formula II, Ar is optionally substituted indolyl or optionally substituted indazolyl.
Examples of the bicyclic heteroaryl groups include indazolyl, quinolinyl, isoquinolinyl and indolyl.
Figures 3A and 3B are synthesis schemes for preparing indolyl and benzofurauyl derivatives.
Preferred heterocyclic radicals for the purposes of this invention are imidazolyl, piperidinyl, pyrrolidinyl, and indolyl.
In another preferred aspect of the invention, Ar is indolyl or substituted indolyl.
Examples of heteroaryl include optionally substituted furyl, pyridyl, pyrimidyl, quinolyl, benzimidazolyl and indolyl.
It is preferred that positions 4 and 6 of the indolyl ring be substituted.
More typically it is selected from pyridyl, pyrimidinyl, quinolyl, isoquinolyl, quinoxalinyl, pyrrolopyridinyl and indolyl.
In another embodiment, R1 is indolyl optionally substituted by fluoro.
The method of claim 5 wherein said substrate is an indolyl ester.
Of them, a furyl, thienyl, pyridyl, or indolyl group is particularly preferable.
Is phenyl optionally substituted with one or two halo substituents, indolyl or thienyl ;.
Then, 150 microliters of a chromogen indicator ( bromo-chloro indolyl phosphate / nitro blue tetrazolium ) were added to the matrix.
