Examples of 'intracellular domain' in a sentence
Meaning of "intracellular domain"
refers to the portion of a cell, specifically the area within the cell membrane. It is often used in biology and biochemistry to describe the region where certain cellular processes occur
How to use "intracellular domain" in a sentence
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intracellular domain
Double underlining shows the intracellular domain.
The intracellular domain is thought to be responsible for signal transduction.
Most of them work through the intracellular domain.
There is an intracellular domain featuring a conserved kinase region and a transmembrane domain.
The isolated polypeptide may comprises an intracellular domain.
Some also contain an intracellular domain like shown in the image.
The isolated polypeptide may comprise an intracellular domain.
Proteins with a long intracellular domain may collide with a fence formed by cytoskeleton filaments.
This uptake was related to induced phosphorylation of its intracellular domain.
Fragments consisting of the intracellular domain may also be useful.
The intracellular domain may comprise at least a portion of three or more cytoplasmic signaling domains.
The enzymatic activity can also be due to an enzyme associated with the intracellular domain.
Intracellular domain interactions with other components will also be targets for drug screening.
The enzymatic activity can also be located on an enzyme associated with the intracellular domain.
The intracellular domain of this receptor is associated with the tyrosine kinase proteins activity.
See also
A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.
Each intracellular domain may be derived from one or more naturally occurring polypeptide signalling sequences.
In an instance the inhKIR intracellular domain comprises an ITIM sequence.
The intracellular domain may comprise an Fc receptor or a portion thereof.
Insertion of the NIS within an intracellular domain of the protein is preferred.
The intracellular domain may comprise at least a portion of LIGHT.
A number of RTK families have been identified based on sequence homologies in their intracellular domain.
The intracellular domain may comprise at least a portion of ICOS.
Often, this signal transduction acts vÃa a catalytic intracellular domain.
Because the intracellular domain of the receptors of the Ig superfamily Bouchon et al.
Her2 is a transmembrane receptor with an intracellular domain and an extracellular domain.
The intracellular domain has intrinsic serine / threonine kinase activity.
Finally, the carboxy terminal intracellular domain or subregion can be replaced.
They consist of an extracellular domain, a single transmembrane pass and an intracellular domain.
Alternatively the intracellular domain to which the antibody binds has the amino acid sequence NKSQKPYKIDSKQAS.
Generally, CARs comprise an extracellular antigen binding domain and an intracellular domain.
Preferably, the intracellular domain is completely deleted, or individual nucleotides are modified.
The cloned receptor has a single transmembrane domain, an extracellular and an intracellular domain.
Ii a transmembrane domain ; and iii an intracellular domain having no recognisable signalling structure.
In an instance, a FcR-CAR comprises an antigen binding domain and a FcR intracellular domain.
Usually, the intracellular domain of the protein is responsible for signal transduction.
Within another embodiment, the isolated polypeptide disclosed above further comprises an intracellular domain.
The intracellular domain then interacts with, and phosphorylates various intracellular signalling proteins.
Within another embodiment, the isolated polynucleotide disclosed above further comprises an intracellular domain.
In another embodiment, antibodies to the intracellular domain of Serrate are produced.
Of course, the tyrosine kinase of interest can provide the transmembrane domain and / or intracellular domain.
The intracellular domain may comprise at least a portion of NKG2C.
Typically such non-immunoglobulin polypeptides are substituted for the transmembrane and / or intracellular domain of an hVEGFr.
The intracellular domain is linked to a G-protein indirectly linked through a linker.
In one embodiment, a TCAR comprises an antigen binding domain fused to an intracellular domain.
The intracellular domain of all Nectins directly bind to a protein called L-Afadin.
In some embodiments, an endodomain may comprise the human CD3 intracellular domain.
The intracellular domain may comprise at least a portion of a ligand that binds to CD83.
Fasentin is a small molecule inhibitor of the intracellular domain of GLUT1 preventing glucose uptake.
The transmembrane region joins the ligand-binding domain to the Intracellular domain.
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In the educational domain projects under way
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Examples of using Intracellular
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Detecting intracellular electrical activity in both atria
This subsequently elevates intracellular cAMP levels
An intracellular molecule that modulates synaptic concentration
