Examples of 'isoform' in a sentence
Meaning of "isoform"
Isoform (noun): A specific form of a protein, gene, or RNA molecule. Isoforms are slightly different versions of the same protein or gene that are produced by slight variations in genetic sequences or post-translational modifications
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- Any of several different forms of the same protein, arising from either single nucleotide polymorphisms, differential splicing of mRNA, or post-translational modifications (e.g. sulfation, glycosylation, etc.)
How to use "isoform" in a sentence
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isoform
No single isoform appears to have a predominant role.
Each different polymeric form is a different isoform.
This isoform activity is not regulated by calcium.
The level of utilization of each isoform is tissue dependent.
This isoform is a therapeutic target for inflammation.
Avian species have lower quantities of the β isoform.
The iNOS isoform can be induced by inflammatory stimuli.
How to generate a simple isoform diagram.
The brain isoform was implicated in endocytosis in these cells.
We used this phenotype as a proxy for isoform usage.
Isoform delta differs from isoform zeta in being phosphorylated.
The antibody may be an IgG isoform.
This isoform may be especially important for development.
An additional transcript and isoform has not been fully characterized.
Isoform alpha differs from isoform beta in being phosphorylated.
See also
Modulation of isoform levels by engineering.
Isoform functionality is dependent on αβ composition.
We conclude that this acidic isoform is the active principle.
Isoform control is indicated in gray.
Peaks containing the b isoform are kept for further processing.
Research concerns on nuclear actin are usually focused on isoform beta.
The rFSH may be present as a single isoform or as a mixture of isoforms.
Little is known about the regulatory characteristics of this isoform.
Each isoform is named according to the tissue in which it was first detected.
This invention relates to the production of isoform specific antibodies.
The alpha isoform is well characterized in terms of its role in inflammation.
Also included are derivatives of the prion protein isoform PrPSc.
The endothelial isoform is involved in the physiologic regulation of blood pressure.
It gives quantitative results on every single isoform in each fraction.
Time course of production of isoform b on incubation of a mixture of isolated isoforms a and c.
In addition splice variants have been described for each isoform.
The relative activities of each isoform are compared to assess compound selectivity.
The response data are as predicted by the isoform ratio data.
Each isoform of human sirtuin is known to have different substrate specificity.
Hybridomas are screened with one isoform that occurs widely in patients.
These mice express the longest human tau protein isoform.
Its isoform synapsin IIb may have a similar but weaker effect.
In most cases several in vivo assays were performed on each isoform preparation.
Mutations that alter function and isoform expression of tau lead to hyperphosphorylation.
We only have evidence of protein expression for the long isoform.
The amounts or concentrations of each subunit isoform independently can be predetermined or known.
The wound macrophage and keratinocyte possess the iNOS isoform.
An isoform is one of a family or collection of related proteins derived from a single gene.
Identification and relative quantification of each isoform in each brain sample.
The inducible isoform is neither stimulated by calcium nor blocked by calmodulin antagonists.
The clones were also analyzed by isoelectric focusing to determine isoform distribution.
The frameshift leads to a protein isoform with a different carboxy terminal sequence.
It will be important to characterize the activity and expression pattern of each isoform.
One isoform lacks the intermembrane region and is secreted outside the cell.
Alternatively spliced transcript variants encoding the same isoform have been identified.
