Examples of 'isoxazolyl' in a sentence
Meaning of "isoxazolyl"
isoxazolyl (noun) - a chemical term used to describe a specific molecular structure or compound that contains an isoxazole ring
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- The univalent radical derived from isoxazole
- Used attributively to describe a class of semisynthetic penicillins that contain an isoxazole group
How to use "isoxazolyl" in a sentence
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isoxazolyl
C is optionally substituted oxazolyl or optionally substituted isoxazolyl.
Isoxazolyl is the univalent radical derived from isoxazole.
Preferred heteroaryl groups are isoxazolyl and pyridinyl.
R1 is isoxazolyl substituted by at least one methyl.
Y may be an optionally substituted isoxazolyl.
Other substituents on the isoxazolyl group may be incorporated in an analogous manner.
An example of hetAr3 includes an isoxazolyl ring.
The substituted isoxazolyl is preferably bonded at its 3-position to the phenyl depicted in formula I.
Represents a thiazolyl group or an isoxazolyl group ;.
Preferred are thienyl, furyl, isoxazolyl and pyridyl optionally substituted, for example, by methyl.
Further particular heteroaryl groups are pyridinyl, imidazolyl, isoxazolyl and pyrazolyl.
The substituted isoxazolyl compounds disclosed herein preferably selectively inhibit cyclooxygenase-2 over cyclooxygenase-1.
Examples of preferred heteroaryl groups are pyridyl, thienyl, isoxazolyl and furanyl.
An isoxazolyl group is found in many beta-lactamase-resistant antibiotics, such as cloxacillin, dicloxacillin and flucloxacillin.
Specific heteroaryl groups of interest include pyridinyl, pyrazolyl, imidazolyl and isoxazolyl.
See also
Values of Het6 that may be mentioned include isoxazolyl and tetrahydropyranyl.
A compound as claimed in Claim 1 wherein R represents optionally substituted isoxazolyl.
Representative examples of A groups include fused isoxazolyl and pyrazolyl rings such as those shown below,.
In one embodiment, Ar is optionally substituted isoxazolyl.
Oxazolyl group, isoxazolyl group, and isothiazolyl group are preferable, and isoxazolyl group is more preferable.
Among the mono-substituted substituents, the preferred substituents substituted on the isoxazolyl ring is lower alkyl.
The substituted isoxazolyl wherein R20 is hydrogen is preferred.
In certain embodiments, Cy1 is an optionally substituted thiazolyl or isoxazolyl group.
An isoxazolyl group which may be substituted by a C1-6 alkyl group, and.
In another embodiment of the present invention, B is isoxazolyl.
D ' isoxazolyl or thiazolyl, wherein said heterocyclic rings may be unsubstituted or substituted by C ₁ - C ₆ alkyl ;.
A compound as claimed in Claim 4 wherein R represents isoxazolyl optionally substituted by methyl.
Preferred examples for 5 - or 6-membered monocyclic heteroaryl are are thiophenyl and isoxazolyl.
In some embodiments, Cy1 is isoxazolyl substituted with 1 or 2 groups independently selected from R11.
In a further embodiment, A represents isoxazolyl.
A compound according to claim 16 wherein R1 is CN, NO2, substituted pyrazolyl, substituted oxazolyl or substituted isoxazolyl.
The compound of claim 3, wherein R ₂ is selected from thienyl, isoxazolyl and pyrazolyl.
Heteroaryl groups selected from pyridyl, thienyl, quinolyl, benzodioxanyl, benzodioxolyl and isoxazolyl groups ;.
Preferred heteroaryl groups include pyrazinyl, thienyl, pyridyl, pyrimidinyl, isoxazolyl and isothiazolyl.
The seed of claim 1 wherein A is pyrazyl, oxazolyl, or isoxazolyl.
In certain embodiments of formula I, Rg is isoxazolyl.
It is known that the resistance profile of CoNS can exceed 90 % for isoxazolyl penicillin.
Examples of unsubstituted 5-membered monocyclic heteroaryl include imidazolyl, oxazolyl, thiazolyl, pyrazolyl, isoxazolyl and isothiazolyl.
According to another aspect, Cy1 is an unsubstituted isoxazolyl group.
In certain aspects, Cy1 is an optionally substituted isoxazolyl group.
In a particularly preferred embodiment, Q2 represents an isoxazolyl ring.
Suitable values for the substituent R3 include phenyl, furyl and isoxazolyl.
The compound of claim 1, wherein R9m * is unsubstituted or substituted isoxazolyl.
The method of claim 1 or 2, wherein C is oxazolyl or isoxazolyl.
