Examples of 'k-ras' in a sentence
Meaning of "k-ras"
K-Ras is a noun that refers to a specific type of protein involved in cell signaling pathways and often associated with cancer development
How to use "k-ras" in a sentence
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k-ras
The biology of the k-ras model is markedly different.
The research focused on a molecular switch called K-Ras.
K-ras mutations are one of the early genomic changes in the carcinogenesis.
In some examples the sample is determined to have wild type K-Ras.
KRAS produces a protein K-Ras that regulates cell proliferation.
The two cell lines have the wild protein K-Ras.
A disease or condition related to a mutant K-ras polypeptide may be a cancer.
Mutations in the K-ras gene are found in adenocarcinoma of the digestive system.
In some examples the Ras mutation is a K-Ras mutation.
In some examples the K-Ras mutation is KA-Ras mutation.
We have created two germline mutations of the K-ras gene.
The KRAS gene produces proteins called K-Ras that influence when cells divide.
These effects were independent of the mutation status of the genes encoding EGFR or K-Ras.
In certain embodiments, a specific binding agent to a mutant K-ras polypeptide is an antigen binding region.
Examples of nucleic acid that can contain a point mutation indicative of a colorectal cancer include K-ras.
See also
The cancer may be K-Ras mutant cancer.
In a particular embodiment the mutation is in exon 1 of K-Ras.
In some examples the K-Ras mutation is KB-Ras mutation.
In certain embodiments disclosed herein, a disease or condition related to a mutant K-ras polypeptide is a cancer.
K-ras mutations and anti-EGFr antibody therapy.
Therefore, new inhibitor having the ability of effectively inhibiting K-ras activity is required.
In some examples the K-Ras mutation is a combination of KA-Ras mutation and a KB-Ras mutation.
In some embodiments, the sample is determined to have wild type K-Ras.
These results implied that K-Ras mediated p53 suppression would be achieved through novel pathway.
In certain embodiments, the cancer cells have a mutated K-Ras gene.
Meanwhile, K-ras was still at membrane level as in normal cells.
These results suggested that p53 could be useful for K-Ras specific drug delivery system.
In some embodiments, a gene having a point mutation includes K-ras.
All of them had the K-ras gene mutated.
To address how K-ras induce Snail, the engagement of AKT was examined.
In some embodiments, the Ras mutation is a K-Ras mutation.
In certain embodiments, a K-ras mutation is detected by detecting the mutant K-ras polynucleotide.
The tested system is the identification of mutant K-ras codon 12 alleles.
Methodology / comparability issues K-Ras mutations " override " benefit in patients with EGFR gene amplification.
The method of claim 7 wherein the target nucleic acid is a K-ras sequence.
In certain embodiments, a K-ras mutation is detected.
About 30 percent of lung adenocarcinomas are brought about by a mutation in the K-ras proto-oncogene.
MUC4 regulation by K-ras in pancreatic carcinogenesis remains unknown.
Specific primer pairs which can be used for PCR amplification of K-Ras exon 1 include,.
The K-ras mutation score can be measured by quantitative allele-specific PCR.
FIG . 7 shows conditions required to activate ATR in stabilizing K-Ras induced Snail.
The genomic wild-type K-ras nucleotide sequence is found at Genbank Accession No.
In another embodiment, said nucleic acid sequence contains mutant K-ras DNA.
For the G12D mutation of the K-ras gene coding for resistance to Erlotinib and Gefitinib,.
Registers the discussed lung tumors, molecular typing of EGFR mutations, ALK transpositions and K-ras mutations.
Mutations in K-Ras occur in approximately 90 % of pancreatic cancers.
At the molecular level, they are said to exhibit a higher frequency of k-ras mutations ( 8 ).
In some embodiments, the K-Ras mutation is KA-Ras mutation.
The K-Ras and p53 genes may be involved in the oncogenesis.
In some embodiments, the K-Ras mutation is KB-Ras mutation.
