Examples of 'kynurenine' in a sentence
Meaning of "kynurenine"
kynurenine (noun): An amino acid produced during the decomposition of proteins, important in such processes as the biosynthesis of tryptophan
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- A metabolite, 2-amino-4-(2-aminophenyl)- 4-oxo-butanoic acid, that is an intermediate in the conversion of tryptophan to niacin.
How to use "kynurenine" in a sentence
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kynurenine
The kynurenine values were determined with será.
In said method the level of kynurenine in saliva is determined.
Kynurenine is also associated with tics.
The present invention relates to the kynurenine pathway.
Consequently kynurenine synthesis could be induced in individuals with obesity.
The primary product of the liver enzyme tryptophan dioxygenase is kynurenine.
Kynurenine and ester of the carboxylic group with retinol.
It is a formylated derivative of kynurenine.
Kynurenine can turn into kynurenic acid or quinolinic acid.
Such a kit comprises means for the determination of kynurenine in saliva.
Kynurenine and other breakdown products are generated by this degradation.
By preparing a standard curve the concentration of kynurenine in each sample could be determined.
Kynurenine undergoes deamniation in a standard transamination reaction yielding kynurenic acid.
Chromophores are derived herein from naturally occurring kynurenine and derivatives thereof.
Kynurenine is the first key branch point intermediate in the pathway.
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A color reagent was prepared and a dilution of a standard solution of kynurenine was also prepared.
High levels of kynurenine have been measured in people with depression and mental illness.
Picolinic acid is a catabolite of the amino acid tryptophan through the kynurenine pathway.
The kynurenine values were substantially higher than the values measured in será of normal patients.
The compounds of the present invention showed an inhibitory effect on the production of kynurenine.
The relative value of kynurenine may preferably be interpreted together with other clinical parameters.
In recipients with primarily functionless grafts the preoperative elevated kynurenine levels did not change.
The level of kynurenine reflects the degree of IDO activation.
Cells were assessed for IDO protein expression by immunoblotting and for kynurenine production.
These findings give evidence for the importance of kynurenine activity also in clinical renal transplantation.
No Kynurenine could be detected.
These results suggest that inhibition of IDO suppresses the production of kynurenine and induces immunity.
Combined measurement of kynurenine and kynurenic acid by HPLC with external standardisation.
Nitrogen-containing heterocyclic compound having inhibitory effect on production of kynurenine.
The role of kynurenine formamidase I is unknown.
When inflammation occurs, quinolinic acid is produced in excessive levels through the kynurenine pathway.
Figure 2 is an evaluation of normal kynurenine values in the serum of healthy control.
Thus, the kynurenine pathway is often systematically up-regulated when the immune response is activated.
Nitrogen-containing heterocyclic compound having kynurenine production inhibitory activity.
Then, they gave the mice a daily injection of kynurenic acid, the breakdown product of kynurenine.
Figure 6 shows the stability of kynurenine after taking the sample from patients.
Kynurenine is the first degradation product of tryptophan after N-formyl kynurenine.
Among the active metabolites of this pathway are tryptophan itself, kynurenine and kynurenic acid.
Wild-type adults excreted kynurenine but adults with salmon-colored eyes excreted tryptophan.
IDO is a single-chain oxidoreductase that catalyzes the degradation of tryptophan to kynurenine.
Quinolinic acid is a downstream product of the kynurenine pathway, which metabolizes the amino acid tryptophan.
Niacin also referred to as vitamin B3, is synthesized from tryptophan through quinolinic and kynurenine acids.
Trp is broken down into three pathways, kynurenine path, serotonergic path and tryptamine path.
The kynurenine pathway of P. aeruginosa could be a new therapeutic target.
Its complex metabolisation vía kynurenine leads to the production of NAD+.
Microdialysate samples were collected for 240 min after administration of kynurenine.
The standard solution of kynurenine was prepared by using L-kynurenine sulfate.
These enzymes include monoamine oxidase, rotenone-insensitive NADH-cytochrome c-reductase, kynurenine hydroxylase and fatty acid Co-A ligase.
Dysregulation of kynurenine metabolism and abdominal fat, a source of inflammation in HIV.
Ommochromes are metabolites of tryptophan, via kynurenine and 3-hydroxykynurenine.
