Examples of 'lead compound' in a sentence
Meaning of "lead compound"
lead compound ~ a chemical compound that is primarily responsible for the activity or effect of a drug or substance
How to use "lead compound" in a sentence
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lead compound
It is the lead compound of the imidazoline family.
An in vivo evaluation confirmed the promising activity of our nucleosidic lead compound.
The preferred lead compound was lead nitrate.
Nucleotides shown in bold are those that differ compared to the lead compound.
A lead compound may arise from a variety of different sources.
The binding affinity for each lead compound is calculated as follows.
A lead compound may be a preferred compound among a plurality of candidate compounds.
Currently they are looking to find a lead compound in order to continue these studies.
Finding a lead compound is the first step in making a new drug to treat a disease.
Even a molecule with weak binding may be a useful lead compound for further investigation and development.
A proprietary lead compound is currently included in all assays as a positive control.
Structural changes to improve ADMET properties often alter the pharmacology of a lead compound.
A suitable soluble lead compound is used for adjusting the amount of lead.
Among these metals, preferable is lead compound.
Examples of the lead compound include lead octylate and lead naphthenate.
See also
A method according to claim 2 wherein the inorganic cocatalyst is a lead compound.
The first lead compound is in formal preclinical development for therapeutic application against psoriasis.
A combination according to claim 2 wherein the lead compound is lead nitrate.
Beads with the desired lead compound activity are then examined by Raman spectroscopy.
A process according to claim 2, wherein the soluble lead compound is lead acetate.
In some embodiments, a lead compound is a preferred compound among a plurality of candidate compounds.
Unfortunately, growth inhibition screens have provided very limited lead compound diversity.
A plant-derived morphinan as a novel lead compound active against malaria liver stages.
A process according to claim 11, wherein the catalyst modifier is a lead compound.
A method of identifying a therapeutic lead compound that modulates activity of a cytoskeletal system, said method comprising,.
When using the in vitro assays, a much greater chance of finding a lead compound is maintained.
A method of identifying a lead compound useful for the treatment of Alzheimer 's Disease comprising,.
However, a dose-response curve for the lead compound was determined.
Researchers found that a lead compound induces the expression of the immunosuppressive cytokine TGF-b from DC.
In a preferred mode of implementation, the material is lead or any lead compound (lead salts… ).
The company 's lead compound is now in Phase II clinical testing.
The drug is Immutep 's lead compound.
The platform can be used in lead compound profiling studies against C. pneumoniae infection.
FIG . 7 is a flow chart of a modification procedure for a lead compound ligand.
A lead compound can be chemically modified, e.g. derivatized, to improve activity and specificity.
However, the low microsomal stability of the lead compound has limited its use in vivo.
The pharmaceutical lead compound may not inhibit binding of cadherin-11 to its counter-receptor.
Positive phase 3 results for Vesneo ™ confirmed potential of Nicox 's lead compound.
These results make NRG-1 promising as a lead compound for the treatment of heart failure.
Tetra-ethyl lead, known as TEL. Success finally came with a lead compound.
Of the lead compound releases, 76 percent were sent off-site to disposal.
Bionure initiates a Phase 1 clinical trial of its lead compound BN201 in the United Kingdom.
It became the lead compound in research leading to the discovery of chlorpromazine . [ 44 ].
A process according to any of claims 11 or 12, wherein the lead compound is red lead oxide.
A lead compound i . e.
In initial studies, some have 1-2 log greater activity than the parent lead compound.
OR141 is the lead compound of a family of benzophenazine-type PS discovered at UCLouvain.
Soluble LAG3, in a dimeric recombinant form called LAG-3Ig is now Prima BioMed's lead compound.
NSI-189 is the lead compound in Neuralstem 's neurogenic small molecule program.
Sensorion intends to integrate measuring prestin in the clinical trial of its lead compound SENS-401 . ".
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