Examples of 'leader sequences' in a sentence
Meaning of "leader sequences"
leader sequences: In the context of genetics or biology, leader sequences are specific DNA or RNA sequences found at the beginning of a gene that are important for transcription and translation processes
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- plural of leader sequence
How to use "leader sequences" in a sentence
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leader sequences
Comparison of the leader sequences of several lantibiotics.
Leader sequences are cleaved off during maturation.
The identification of other leader sequences is known in the art.
These leader sequences were chosen as typical of antibodies.
The amplified sequences also contained the leader sequences.
Such leader sequences are well known in the art.
These domains represent potential transmembrane regions or hydrophobic leader sequences.
Leader sequences may be synthesised based on known sequences.
The term also includes leader sequences or leader peptides.
Such leader sequences can act to enhance translation.
We also tested the effect of adding leader sequences to the polypeptide.
Leader sequences have been shown to influence translation dramatically.
Note that no additional leader sequences are required in this vector.
Leader sequences may not be required for expression in a bacterial cell.
The arrowhead shows the cleavage site for hydrophobic leader sequences.
See also
Their leader sequences were used for expression of humanized mAbs.
Sequences for these and other leader sequences are well known in the art.
Leader sequences are underlined.
Other control elements useful in yeast expression are terminators and mRNA leader sequences.
Their leader sequences are as follows.
Secretory signal sequences or signal sequences or secretion leader sequences encode secretory peptides.
Processing of the leader sequences will result in secretion of the tridecapeptide.
The truncated form is relegated into a vector with the appropriate promoter and secretion leader sequences.
A variety of specific leader sequences can be used with the polynucleotides.
It enables the concatenation of the human VH and cynomolgus VH leader sequences.
The cleaved leader sequences have no effect on the final antibody properties.
Preferred DNA constructs encoding leader sequences are as shown in Figs.
Such leader sequences are obtained from several genes of either plant or other sources.
Genomic clones containing the VI and VH leader sequences were identified as well.
Leader sequences are also known as signal peptides and are well known in the art.
The following three leader sequences were considered,.
The leader sequences are encircled and the complimentarity determining regions are shown in boxes.
It may be beneficial to include 5 ' leader sequences in the expression cassette construct.
RNA leader sequences are found upstream of the first gene of amino acid biosynthetic operons.
One interpretation is that chain 1 has two alternative leader sequences.
A library of leader sequences is used to optimize the combination of leader sequence and mutant.
Fragments include, but are not limited to, sequences without the leader sequences.
A procaryotic leader sequences for protein excretion of functional antibody fragments into bacterial periplasma.
However, no significant homology exists between the leader sequences of these arteriviruses.
Yeast recognizes leader sequences on cloned mammalian gene products and secretes peptides bearing leader sequences.
The present invention employs truncated leader sequences from a yeast a-factor gene.
Leader sequences can be removed by the host in post-translational processing.
Three different leader sequences were considered,.
Accordingly, the disclosure relates to antibodies as described herein without the leader sequences.
Examples of leader sequences are reviewed by Schatz et al.
Additionally, heterologous leader peptides may be substituted for the endogeneous leader sequences.
Alternatively, leader sequences are employed to provide improved expression.
The expression cassettes may additionally contain 5 ' leader sequences in the expression cassette construct.
For example, leader sequences and fusion partner sequences are expression control sequences.
Improved expression and secretion of heterologous proteins in yeast employing truncated alpha-factor leader sequences.
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