Examples of 'levosimendan' in a sentence
Meaning of "levosimendan"
levosimendan (noun): A medication used in the treatment of acute heart failure and other cardiac conditions. Levosimendan helps to improve heart function by increasing the sensitivity of cardiac muscle cells to calcium, leading to enhanced contractions and improved cardiac output
Show more definitions
- A calcium sensitiser used in the management of acutely decompensated congestive heart failure.
How to use "levosimendan" in a sentence
Basic
Advanced
levosimendan
Levosimendan is shown to reduce mortality and hospitalization.
Patients were assigned to receive levosimendan in addition to standard care.
Levosimendan in patients with ischaemic heart disease.
In vivo mechanisms of action for levosimendan are not known.
Levosimendan was well tolerated in all studies.
Hypotension did not develop in both groups during levosimendan infusion.
Salts of levosimendan may be prepared by known methods.
Vasodilatory effect was more pronounced with intravenous levosimendan.
Permeation of levosimendan across human skin in vitro.
Most events resolved either spontaneously or after levosimendan dose reduction.
The use of levosimendan is not supported by clinical experience.
The addition of NaCMC increased the release of levosimendan from buccal tablets.
Levosimendan slightly improved systolic function.
The hemodynamic effects of the active metabolite as such are similar to those of levosimendan.
Levosimendan is useful in the treatment of congestive heart failure.
See also
Some may criticize the use of levosimendan in patients with impaired renal function.
Levosimendan is a cardiac enhancer having both inotropic and vasodilatory effects.
Clinical studies have confirmed the beneficial effects of levosimendan in heart failure patients.
The efficacy of levosimendan was not related to the loading dose amount.
One reason of this might be the lack of loading dose application during levosimendan administration.
Levosimendan is used in an amount as described for the previous preferred embodiment.
These favourable effects suggest that levosimendan is particularly beneficial in the treatment of septic shock.
Levosimendan is a calcium channel sensitizer used in the treatment of decompensated heart failure.
A pharmaceutical composition comprising levosimendan as an active ingredient and alginic acid as a stability improving agent.
Levosimendan is a calcium sensitizer that produces increase in contractility and decrease in systemic vascular resistance.
The formulations have therapeutically and commercially useful concentrations of Levosimendan.
Improved formulations of levosimendan for intravenous administration as infusion or injection and of infusion concentrate.
In a further embodiment of the present invention polymeric micelles containing Levosimendan are prepared.
Levosimendan has been described to have beneficial effects in ventricular remodelling after myocardial infarction.
Another limitation is that baseline QRS width is greater in levosimendan group than dobutamine group.
All levosimendan treated animals survived whereas one animal in the control group died.
For obtaining a liquid composition with the solubilized Levosimendan the following procedures may preferably be used.
The finding that levosimendan did not negatively affect renal function concurs with previous reports.
Degradation products of Levosimendan are detectable.
Levosimendan is a novel inotropic agent that improves cardiac contractility without increasing myocardial oxygen consumption.
The company recently acquired the North American rights to develop and commercialize levosimendan.
It was shown that levosimendan treatment decreased TNF alpha levels.
Secondly, the gastrointestinal absorption of levosimendan is rapid.
This anti-inflammatory effect of levosimendan treatment was explained by various mechanisms.
In cases of chronic use of betablockers, milrinone or levosimendan were chosen.
Levosimendan is represented by the formula,.
As a powerful vasodilator, levosimendan may be a harmful drug.
Levosimendan is a pyridazone-dinitrile derivative.
Pharmacokinetics of levosimendan in man after i . v.
Levosimendan - a heart medicine that could preserve respiratory function.
However, atrial fibrillation was found to increase in the levosimendan group.
Attempts to administer levosimendan in conventional long-acting preparations have been disappointing.
Simendan is a racemic compound made of 2 enantiomers, dextrosimendan and levosimendan.
In this study, levosimendan treatment was also associated with a significant decrease in mortality.
Furthermore, concomitant use of b-blockers did not influence response rates to levosimendan.
