Examples of 'linear epitopes' in a sentence
Meaning of "linear epitopes"
linear epitopes - Specific regions on antigens where antibodies can bind in a straight chain, commonly used in immunology and vaccine development
How to use "linear epitopes" in a sentence
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linear epitopes
In a denatured protein only linear epitopes are recognized.
Linear epitopes can be contiguous or overlapping.
These are known as linear epitopes.
Linear epitopes are formed by a continuous sequence of amino acids in a protein.
This procedure allows the recognition of epitopes for antibodies that react with apparent linear epitopes.
Some epitopes are linear epitopes while others are conformational epitopes.
Those peptides that are recognised are so-called linear epitopes.
The RSV epitopes can be linear epitopes or conformational epitopes.
Linear epitopes are generally at least 6 amino acid residues in length.
However, it is especially preferred to use linear epitopes that are no mimotopes.
By contrast, linear epitopes interact with the ligand based on their primary structure.
The peptide scan ( pepspot assay ) is routinely employed to map linear epitopes in a polypeptide antigen.
Linear epitopes are typically about six amino acids, though this can vary somewhat.
Thus, it appears that only linear epitopes exist in these antigens.
Intact antigen, fragments thereof such as the extracellular domain, or linear epitopes can be used.
See also
Where the antigen is a protein, linear epitopes range from about 5 to 20 amino acids in length.
PGLYRP1 may also comprise linear epitopes.
Figure 10 shows that OppA2 linear epitopes are conserved among pathogenic Borrelia species.
Epitopes formed from contiguous residues ( e.g., amino acid residues ) typically are also called linear epitopes.
In contrast, T cells usually recognize small linear epitopes based on sequential information.
Linear epitopes have a length of between 6 and 20 amino acids, more preferably between 8 and 15 amino acids.
The latter approach is suitable to define linear epitopes of about 5 to 15 amino acids.
These results suggest that MAbs 3C3 and 3E4 recognized partially linear epitopes.
These were found to recognize linear epitopes presented by one synthetic peptide ( Table 4 ).
For linear epitopes such as Kricek ( VNLTWSRASG, SEQ ID NO, 50 ), interchangeability should also be possible.
This breakdown exposes additional linear epitopes to which the 18A1 monoclonal preferentially binds.
Thereby an antibody ( PAB 150 ) to less immunogenic linear epitopes was obtained.
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