Examples of 'major metabolites' in a sentence

Meaning of "major metabolites"

Refers to the primary byproducts or chemical compounds that are produced during the metabolic processes occurring within an organism, often used in the context of pharmacology or drug testing

How to use "major metabolites" in a sentence

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major metabolites
There are two major metabolites in human plasma.
It has been demonstrated recently that the two major metabolites.
All the major metabolites are unhydrolyzed carbamates.
It is unknown whether siponimod or its major metabolites are excreted in human milk.
Three major metabolites of triamcinolone acetonide have been identified.
Biotransformation yields two major metabolites of known structure.
All major metabolites have been shown to be pharmacologically inactive.
The antibody should be able to recognize as many of the major metabolites as possible.
The major metabolites shall be identified and characterised.
The hydrolysed and dehydrogenated voxilaprevir were the major metabolites identified in human plasma.
Three major metabolites were identified in plasma.
Risk assessment in natural surface water systems where major metabolites have potentially formed.
Five major metabolites have been identified.
Many genotoxicity studies have been conducted for the major metabolites of TCE.
The major metabolites shall be identified and characterized.

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The structures of cyclosporine and some of its major metabolites are of the formula,.
Two major metabolites of temoporfin are eliminated into the bile.
Using in vitro metabolism data, concentrations of major metabolites can also be estimated.
No major metabolites are detected in plasma.
Figure 1 Structures of carbamazepine and major metabolites.
The two major metabolites showed negligible pharmacological activity.
Full scan LC-MS analysis was then performed to detect major metabolites.
The major metabolites of esomeprazole have no effect on gastric acid secretion.
Full scan LC-MS analysis is then performed to detect major metabolites.
Major metabolites are distributed over the entire haircoat of the dog.
Moreover, cysteine and cystine have been identified as major metabolites of NAC.
Five major metabolites were detected all having been shown to be pharmacologically inactive.
Action and effects of medicines, endocrine disruptors and major metabolites in coastal Mediterranean waters.
Eight other major metabolites remained unchanged during ethanol infusion.
For metabolite detection, Q1 full scans are used as survey scans to detect the major metabolites.
The major metabolites of this pathway are homovanillic acid and dihydroxyphenylacetic acid.
For metabolite detection, Q1 full scans were used as survey scans to detect the major metabolites.
DDE and DDD are also the major metabolites and breakdown products in the environment.
The 4-oxo and 4-hydroxymetabolite epimeric pair are the major metabolites with.
The major metabolites of coumarin in vitro, viz.
High concentrations of bupropion and its major metabolites did not inhibit MAO-A or MAO-B activity.
The major metabolites in body fluids are the 5 hydroxy analog and the acetylamino analog.
It is further reported that the major metabolites of Y-tocopherol were identified as Y-CEHC.
Two major metabolites of sodium Compound 22 sodium salt were identified in hepatocytes.
Also after i . d . administration no major metabolites are present.
Esomeprazole or its major metabolites do not show any tendency to accumulate with once-daily dosing.
Figure 3 shows the structure of another of the major metabolites of vancomycin, CDP-II.
Metabolism, Major metabolites of doxycycline have not been identified.
Figure 2 shows the structure of one of the major metabolites of vancomycin, CDP-I.
Bupropion and its major metabolites had no significant affinity for the 5HT transport system.
The pharmacokinetics of nefazodone and its major metabolites are not altered in these “ poor metabolizers . ”.
The major metabolites have been identified as various N - and O-dealkylated products of verapamil.
Distribution Nitroglycerin and its major metabolites are approximately 60 % protein bound.
The major metabolites in humans are a 5-hydroxy analog and an acetamino analog.
M1 and M6 are the two major metabolites of ivacaftor in humans.

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Examples of using Metabolites
Both metabolites were rapidly degraded to carbon dioxide
There are two major metabolites in human plasma
These metabolites appear to be pharmacologically inactive in man
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Examples of using Major
Major liver laceration and active hemorrhage
Growing joblessness is a major challenge for all of us
Some major outstanding contributions were expected soon
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