Examples of 'maleimide group' in a sentence
Meaning of "maleimide group"
maleimide group - This phrase refers to a chemical group with specific properties and characteristics, often used in organic chemistry
How to use "maleimide group" in a sentence
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maleimide group
A lysine residue is covalently linked to the maleimide group.
The functionalized end group is preferably a maleimide group for selective coupling to antibody sulfhydryl groups.
One preferred example of such a group is a maleimide group.
Reaction of maleimide group with thiol group quickly takes place whereupon they form a covalent bond.
The electrophilic group is a maleimide group.
A reactive maleimide group was introduced on the amino groups of avidin with SMCC.
Preparation of the complex with maleimide group conjugated thereto.
A terminal bismaleimide moiety refers to a moiety having a terminal maleimide group.
This is particularly appropriate where unreacted maleimide group are present prior to the quenching step.
The maleimide group of avidin was reacted with the SH groups of the reduced antibody.
The linking group can be derived from a maleimide group.
To achieve this, a maleimide group can be introduced on a drug, for example psoralenes compounds.
A lysine residue may be covalently linked to the maleimide group.
For this reason, peroxidase into which a maleimide group is preliminarily introduced is conveniently used.
For example, a targeting moiety may contain an active ester or a maleimide group.
See also
In some embodiments, a maleimide group is used.
Preferably, the biocompatible linking group is an ester group and / or a maleimide group.
This crosslinker has an NHS-ester and a maleimide group connected with a spacer arm.
Accordingly, in some embodiments, the drug will be linked to the antibody vÃa a maleimide group.
Alternatively, one can provide for a maleimide group which with thiophosphate will form the alkylthioester.
The antibody molecule of claim 9, wherein a lysine is covalently linked to the maleimide group.
The PMPI molecules also include a maleimide group 42 that is reactive with a thiol group.
Particularly, it relates to a novel phospholipid derivative having a polyalkylene glycol moiety having a maleimide group.
Examples thereof are crosslinking agents having a maleimide group and a succinimide group.
Examples of the radical polymerizable group include a ( meth ) acryloyl group, a vinyl group, and a maleimide group.
The linker may further comprise a maleimide group for linkage to the antibody, e.g., maleimidocaproyl.
Schemes 2 and 3 show the construction of a Linker unit having an electrophilic maleimide group.
The maleimide group may react with, for example, an SH group.
A certain group may therefore intervene between the maleimide group and the peroxidase.
The maleimide group modification rate was also calculated from 1H-NMR analysis.
One can also use activated biotin attached through a maleimide group to cysteine residues.
To attach branched PEG molecules, a lysine residue is preferably covalently linked to the maleimide group.
The crosslinker has an NHS ester separated from a maleimide group by benzoic acid.
The method of claim 25, wherein said mercapto-reactive linker comprises a maleimide group.
The synthesis of an illustrative Stretcher having an electrophilic maleimide group is illustrated in Schemes 8-9.
A method according to claim 4, wherein said reactive group is a maleimide group.
It is then treated with SMP ( Pierce ) in order to introduce a maleimide group.
Preferably, the cross-linking reagent contains both an N-hydroxysuccinimide ester group and a maleimide group.
In one embodiment, the group G1 is an alkyl maleimide group.
In a preferred embodiment, G1 comprises a maleimide group.
The method of claim 18 or 19, wherein said reactive group is a maleimide group.
The method according to any one of claims 20-24, wherein said reactive group is a maleimide group.
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