Examples of 'malonyl-coa' in a sentence
Meaning of "malonyl-coa"
malonyl-coa (noun) - a molecule that plays a key role in the biosynthesis and degradation of fatty acids in living organisms. It is an important precursor in the synthesis of fatty acids
How to use "malonyl-coa" in a sentence
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malonyl-coa
A positive control included racemic malonyl-CoA.
Measurement of malonyl-CoA production inhibition in experimental animals.
In a particularly preferred embodiment, the carbonaceous substrate is malonyl-CoA.
The potential binding site of malonyl-CoA was also identified.
The strains produce fatty alcohols independent of of malonyl-CoA.
When conditions favor fat storage, malonyl-CoA is produced as an intermediate in lipogenesis.
The second suggested that two cinnamate units are coupled by malonyl-CoA.
Three malonyl-CoA moities are then added and cyclized to introduce a phenol ring.
Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors.
In one aspect, malonate production is improved by increasing the biosynthesis of malonyl-CoA.
Figure 3 below shows high levels of malonyl-CoA in the tumor tissue compared to the liver.
Disclosed are consensus sequences useful in identifying and constructing malonyl-CoA hydrolases.
The engineered malonyl-CoA hydrolase is integrated onto the chromosome using standard recombination methods.
The second mechanism involved two cinnamate units being coupled together by malonyl-CoA.
Increased malonyl-CoA level pushes the equilibrium over to increase production of fatty acids through biosynthesis.
See also
The over-expression of ACCase in the cytoplasm can produce higher levels of malonyl-CoA.
Malonyl-CoA is a potent inhibitor of fatty acid oxidation.
Flavonoids and caffeic acid derivatives are biosynthesized from phenyl alanine and malonyl-CoA.
Malonyl-CoA is also a key intermediate in the de novo synthesis of lipids.
The second mechanism involves two cinnamate units ativan canada coupled together by malonyl-CoA.
Malonyl-CoA knockout strains are constructed of each of the yeast acyl-CoA synthetases.
The fatty acid biosynthetic pathway involves the precursors acetyl-CoA and malonyl-CoA.
Malonyl-CoA levels may be manipulated using a variety of methods and target enzymes.
When only a single expression vector is used, the vector will typically contain a malonyl-CoA hydrolase gene.
Cytoplasmic malonyl-CoA levels are higher during fatty acid synthesis due to increased activity of ACC.
This would result in increased ACC activity and malonyl-CoA levels.
Malonyl-CoA provides the two-carbon building blocks that are used to create larger fatty acids.
This is a result of decreased activity of ACC which causes a subsequent decrease in malonyl-CoA concentrations.
Example 5 Addition of matBC The matBC genes encode a malonyl-CoA synthetase and a dicarboxylate carrier protein, respectively.
The PUFA synthase competes with these other enzyme systems for the malonyl-CoA.
Certain protists such as Euglena gracilis are capable of malonyl-CoA independent fatty acid biosynthesis.
Erucic acid is produced by elongation of oleic acid via oleoyl-coenzyme A and malonyl-CoA.
The AT domain activates malonyl-CoA and attaches it to the ACP.
Malonyl-CoA levels were markedly increased with FAS inhibition and reduced by TOFA.
Inhibition of MCD would acutely raise malonyl-CoA levels.
Malonyl-CoA allosterically inhibits carnitine palmitoyltransferase I, and thereby inhibits LCFA transport into the mitochondria.
Formation of malonyl-CoA.
Affecting ACC affects the rate of acetyl-CoA conversion to malonyl-CoA.
Inhibited by malonyl-CoA.
Malonyl-CoA and malonylcamitine ( levels increase with increasing levels of triglycerides in liver ) ;.
Biosynthesis of malonyl-CoA.
Malonyl-CoA then reacts with another acetyl-CoA to form the desired acetoacetyl-CoA.
The main precursors for fatty acid biosynthesis are malonyl-CoA and acetyl-CoA.
Examples 4-5 demonstrate elevation of malonyl-CoA levels through reduced utilization and simultaneous enhanced production.
In this example the specificity of borAT4 is directed from methyl-malonyl-CoA towards malonyl-CoA.
Acetyl-CoA and malonyl-CoA undergo a Claisen condensation with lose of carbon dioxide to form acetoacetyl-CoA.
In an ATP dependent enzymatically catalyzed reaction, acetyl-CoA is carboxylated to form malonyl-CoA.
ACCase is a biotinylated enzyme that converts acetyl-CoA to malonyl-CoA in a 2-step reversible reaction.
Malonyl-CoA is converted to malonyl-ACP by the malonyl-CoA, ACP transacylase.
Amount of phloroglucinol produced by PKS1 from Malonyl-CoA.
