Examples of 'megakaryocyte' in a sentence
Meaning of "megakaryocyte"
Megakaryocyte (noun) - A large bone marrow cell with a lobulated nucleus, responsible for the production of blood platelets
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- A large cell, found in bone marrow, responsible for the production of platelets.
How to use "megakaryocyte" in a sentence
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megakaryocyte
Megakaryocyte regulation occurs at multiple cellular levels.
This is believed to be due to an increased rate of megakaryocyte fragmentation into platelets.
A single megakaryocyte can give rise to thousands of thrombocytes.
Compositions and methods for stimulating megakaryocyte growth and differentiation.
The megakaryocyte colony counts of duplicate or more assays were averaged.
The present invention also provides gene coding for megakaryocyte differentiation factor.
No erythroid or megakaryocyte colonies were observed in the control animals.
The present invention further provides a pharmaceutical composition comprising a megakaryocyte differentiation factor as an effective ingredient.
Megakaryocyte produces several thousand.
Cells were analyzed for megakaryocyte surface markers and their ploidy status.
Megakaryocyte quantifications in relation to thrombokinetics in primary thrombocythaemia and allied diseases.
Compositions highly enriched for megakaryocyte progenitor activity are achieved in this manner.
Megakaryocyte colonies were scored when they contained four or more megakaryocytes.
The cell eventually reaches megakaryocyte stage and loses its ability to divide.
Megakaryocyte differentiation factor.
See also
The primary signal for megakaryocyte production is thrombopoietin or TPO.
Megakaryocyte colonies were defined as a group of 3 or more cells.
Determination of Structure of CDNA for megakaryocyte differentiation factor.
The megakaryocyte potentiator of the present invention demonstrates the properties indicated below.
A pharmaceutical composition comprising the megakaryocyte potentiator of claim 1.
Anagrelide inhibits megakaryocyte enhancement of ovarian cancer cell migration at clinically relevant concentrations.
A nucleic acid molecule encoding the megakaryocyte potentiator of claim 1.
The present megakaryocyte potentiator is purified as described in Examples.
Suitably, the telomerase inhibitor inhibits cytokine-independent megakaryocyte growth.
Isolated DNA coding for a megakaryocyte differentiation factor according to any one of the preceding claims.
Monoclonal antibodies for glycoprotein IIb / IIIa were used for megakaryocyte identification.
A megakaryocyte potentiator having the following properties,.
A method for the production of the megakaryocyte potentiator of claim 1 comprising.
One megakaryocyte colony is defined as 3 or more cells.
A megakaryoblast is a precursor cell to a promegakaryocyte, which in turn becomes a megakaryocyte during haematopoiesis.
A megakaryocyte differentiation factor having the following properties ;.
Fig . 6 shows a result of an iselectroric focusing of the purified megakaryocyte differentiation factor.
Second, we study megakaryocyte elongation and rupture in a microfluidic device.
Suitably, the telomerase inhibitor does not inhibit cytokine-dependent megakaryocyte growth.
A megakaryocyte differentiation factor according to claim 1, obtainable from human cells.
Thrombopoietin plays a role in inducing the megakaryocyte to form small proto-platelet processes.
A megakaryocyte differentiation factor according to any one of claims 6 to 9 which is glycosylated.
In other instances, administration of the telomerase inhibitor inhibits cytokine-independent megakaryocyte growth.
Note, megakaryocyte potentiator activity is measured using the method described below.
Thereafter, observation was made under a microscope to see whether megakaryocyte proplatelets had formed.
When a megakaryocyte matures, its cytoplasm breaks up, forming several thousand platelets.
Flt-3 ligand only has marginal effects on erythroid and megakaryocyte progenitor cells.
Megakaryocyte and platelet production is regulated by thrombopoietin, a hormone produced in the kidneys and liver.
In another aspect, the invention provides a gene coding for such a megakaryocyte differentiation factor.
Moreover, the present megakaryocyte potentiator can also be prepared using genetic engineering techniques.
The pTKs can also be instrumental in the modulation of megakaryocyte and / or platelet adhesion interactions.
As a result, the megakaryocyte differentiation factor belongs to the super family of serine protease inhibitor.
Recent studies show that GSK3beta inhibitor treatment improves neutrophil and megakaryocyte recovery.
The megakaryocyte differentiation factor is useful as a hemopoietic stimulating factor for megakaryocyte-platelet linease.
We detected cells with typical morphological features of erythroid, macrophage, granulocyte, and megakaryocyte precursors.
