Examples of 'mesylate salt' in a sentence
Meaning of "mesylate salt"
mesylate salt - Mesylate salt refers to a type of salt that contains the mesylate ion, often used in organic chemistry for various chemical reactions and synthesis processes
How to use "mesylate salt" in a sentence
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mesylate salt
The product was converted to its mesylate salt.
The mesylate salt is the preferred form of salt.
The sample was converted to its mesylate salt.
The mesylate salt precipitated.
This product was converted to its mesylate salt.
The mesylate salt trihydrate can be prepared by the following method.
The pharmaceutically acceptable salt may be mesylate salt.
The resulting crystalline mesylate salt trihydrate can be further purified by recrystallization.
Preferably said salt is a napadisylate salt or a mesylate salt.
Then the precipitated mesylate salt was collected and dried under vacuum.
Preferred salts include the hydrochloride and mesylate salt.
The mesylate salt can be prepared by treatment with methanesulphonic acid in acetone.
Another pharmaceutically acceptable salt of sertraline is the mesylate salt.
This was converted to the mesylate salt by treatment with methane sulfonic acid in ether.
The compound according to any preceding claim which is the mesylate salt.
See also
Stability of the mesylate salt of the present invention was evaluated under accelerated condition.
The trifluoroacetic acid salt was prepared in a similar manner to the mesylate salt.
Polymorphs of Compound A mesylate salt are highly soluble in water and stable under storage.
Most preferably the paroxetine is present as the hydrochloride salt or the mesylate salt.
The invention provides a mesylate salt of a compound of Formula I.
The methods may involve using Compound I in the form of a tosylate or mesylate salt.
The mesylate salt of the compound of claim 7.
Any salt of DHE may be used but the mesylate salt is preferred.
Crystalline mesylate salt 1 can be isolated from the solvent by filtration.
In a specific embodiment, the pharmaceutically acceptable salt is a mesylate salt.
In one embodiment, the mesylate salt form is partially amorphous.
In another embodiment, the pharmaceutically acceptable salt is the mesylate salt.
In one embodiment, the mesylate salt form is substantially amorphous.
In a further embodiment, the pharmaceutically acceptable salt is the mesylate salt.
In one embodiment, the mesylate salt form is substantially crystalline.
In the preferred embodiment, the pharmaceutically acceptable salt is a mesylate salt.
As disclosed herein, the mesylate salt form may be substantially crystalline.
In addition, a polymorphic transformation was observed for the mesylate salt in aqueous solutions.
As disclosed herein, the mesylate salt form may be substantially amorphous.
The solution was concentrated under vacuum to afford the mesylate salt 1 as a brown solid.
The mesylate salt took up water to some extent, but deliquescence did not occur.
According to table 2, also the mesylate salt benefits from extremely high solubility.
The mesylate salt 1 can crystallize from the solution with or without stirring or seeding.
As disclosed herein, the mesylate salt form may be partially amorphous.
Preferably, the pharmaceutically acceptable salts of sertraline are the hydrochloride salt and the mesylate salt.
Most unexpectedly, the claimed mesylate salt is significantly more bioavailable than the HCl salt.
Accordingly, the present invention permits a more efficient synthesis of the mesylate salt with fewer steps.
The mesylate salt 1 can precipitate from the DCM.
Exemplary pharmaceutically acceptable salts include, for example, the hydrochloric acid salt and mesylate salt.
Examples of useful solvents for crystallizing the mesylate salt 1 are disclosed in Table 1.
In the Dypyrrole compounds of the invention, the pharmaceutically acceptable salt may be mesylate salt.
The disclosure includes a mesylate salt of a compound according to Formula I, IA, or IB.
In one embodiment, DHE is used as the mesylate salt.
Figure 21 shows an AD mesylate salt crystal XRD pattern.
A compound according to Claim 1 which is the hydrochloride, maleate or mesylate salt.
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