Examples of 'metalation' in a sentence
Meaning of "metalation"
metalation (noun) - The process of introducing a metal atom into a molecule, often used in organic chemistry
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- Any chemical reaction in which a hydrogen atom is replaced by one of a metal
How to use "metalation" in a sentence
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metalation
Its use as a strong base is referred to as metalation.
The reaction is a metalation followed by a cyclization.
Both amines affect the regiochemistry of metalation.
Metalation often occurs at the position ortho to these substituents.
Few methods are known for direct or indirect metalation of chlorophylls.
Directed ortho metalation is an important tool in the synthesis of regiospecific substituted aromatic compounds.
At the lower temperatures an acceptable and useful level of metalation was achieved.
Such metalation reactions employing a polar coordinator are known to those skilled in the art.
This method of synthesis is generally known as a directed ortho metalation reaction.
A modifier may be reacted after the metalation reaction which follows hydrogenation of the copolymer.
No other órgano metallic compounds are suitable for this metalation step.
Metalation of Toluene.
Directed ortho metalation - cross coupling links.
However, in the presence of tertiary diamines and bridgehead monoamines, metalation proceeds rapidly and smoothly.
The metalation was essentially completed within 2 minutes.
See also
In a most preferred embodiment, the melt metalation is performed in an extruder.
The metalation introduces a carboxylic acid or ester adjacent to the protected 4-aminopyridine.
In a preferred embodiment the metalation is carried out in a non-polar solvent.
The metalation reaction is quenched after 15 minutes by using an excess of the indicated electrophile.
Additionally, the present method avoids cumbersome metalation of the aromatic moiety.
Metalation occurred within 5 minutes.
One approach consists of a directed metalation as shown in Scheme 2.
Remarkably, with this base only 1.1 equivalents are required to achieve a complete metalation.
In the cases of N-substituted pyrroles, metalation of the carbons is more facile.
Using the metalation - cross coupling approach, the synthesis of the reassigned dengibsinin ( 7a ) is presented.
The carbon-heteroatom bond forming reaction is selected from halogenation, oxidation, silylation, and metalation.
Metalation was first observed in the laboratory by Edward Frankland during a synthesis of diethylzinc in 1849.
These include hydrocracking, hydrogenation, alkylation ( SN2 ), oxidation, metalation and nucleophilic aromatic substitution.
Metalation of allyldiphenylphosphine and then transmetalation with Ti ( OPri ) 4 gives the titanium intermediate.
Directed metalation of 1,3-disubstituted pyrroles is described above.
The metalation of organic polymers in general is discussed, among others, by A. J.
The metalation of 1-butyne with excess n-butyllithium is discussed by Eberly and Adams in J. Organometal.
