Examples of 'microprojections' in a sentence
Meaning of "microprojections"
microprojections (noun): Small-scale projections or protrusions, often used in technology or medical devices for various purposes such as drug delivery or sensing
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- plural of microprojection
How to use "microprojections" in a sentence
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microprojections
The substrate is adhered or attached to the microprojections.
The spacing of the microprojections may be regular or irregular.
Other coating methods include spraying the coating solution onto the microprojections.
The microprojections may be attached to the substrate by any suitable means.
The drug concentrated in the tips of the microprojections is observed.
The microprojections may be positioned on a base or substrate to form the array.
The projections may be microprojections.
The microprojections are then folded or bent out of the plane of the sheet.
The coating can be applied to the microprojections using known coating methods.
The microprojections have a substantially dry coating thereon which contains the active agent.
The device has a piercing depth limiter associated with at least a portion of the microprojections.
The length of the microprojections are substantially longer than the predetermined depth of penetration.
The microprojection array according to any of the previous claims wherein said microprojections are microneedles.
Each of the microprojections is located at a node of a regular pattern ;.
Therefore, it may be preferable to only coat the tips of the microprojections.
See also
The device has a plurality of skin piercing microprojections which have a dry coating of the drug.
The microprojections project on one side only of said sheet ;.
The device has a plurality of stratum comeum-piercing microprojections extending therefrom.
The coating 50 on the microprojections can be formed by a variety of known methods.
A mold is provided, the mold comprising a plurality of cavities for forming the microprojections.
Formulations for coated microprojections containing non-volatile counterions.
The device includes a member having a plurality of skin-piercing microprojections extending therefrom.
Furthermore, the microprojections may contain means for receiving a greater amount of coating.
Generally, the coating thickness is an average thickness measured over the surfaces of the microprojections.
The microprojections may have any suitable shape including, but not limited to polygonal or cylindrical.
For example, the degradation rate and delivery for degradable microprojections may be affected.
The mesh of the array of microprojections in the embodiment shown in FIG . 1 is square.
The term " pattern coating " refers to coating an agent onto selected areas of the microprojections.
In the embodiment shown, these microprojections have a perforated end wall 4.
That is, when substantially dry, the coating is not easily dislodged from the microprojections.
The microprojections typically have a width and thickness of about 5 to 50 microns.
This hydrophilic agent-containing coating could be applied prior to bending the, microprojections down.
The microprojections have a width and thickness of about 5 micrometers to about 50 micrometers.
FIGURE 5 is an illustration of one method of forming microprojections.
FIGURES 4A-4C are illustrations of shapes of dried microprojections obtained with various methods of preparation.
Similarly, " microprojection array " denotes a two-dimensional or three-dimensional arrangement of microprojections.
The microprojections further have a width designated " W " in Fig.
That is, separate coatings are applied to the individual microprojections 10.
The microprojections had a triangular shape with a length 545 µm.
Pattern coating can also be employed to coat the microprojections 34.
A plurality of microprojections 70 are shown located around a plurality of openings 78 in sheet 76.
When that twisting occurs, member 184 moves downward pressing the microprojections against the skin.
The microprojections are not visible in FIGS . 2A-2D due to their small size.
The coating 18 may partially or completely cover the microprojections 12.
A delivery device having stratum corneum piercing microprojections coated with a formulation of hPTH ( 1-34 ) was prepared.
For example, the coating 35 can be in a dry pattern coating on the microprojections 34.
In one embodiment of the invention, the microprojections have a projection length less than 1000 microns.
As shown in FIGURE 1, the microprojection array 5 includes a plurality of microprojections 10.
Figure 2 illustrates the microprojection array 5 wherein the microprojections 10 have been coated with a biocompatible coating 50.
As shown in FIG . 1, the microprojection array 5 includes a plurality of microprojections 10.
