Examples of 'microsomes' in a sentence
Meaning of "microsomes"
'Microsomes' are cell organelles found in the cytoplasm that contain enzymes and are involved in the metabolism of drugs
Show more definitions
- plural of microsome
How to use "microsomes" in a sentence
Basic
Advanced
microsomes
Hepatic microsomes were isolated from individual livers.
Articaine is additionally metabolised in the liver microsomes.
Microsomes and microparticles also can be used.
Metabolic stability in mouse and rat microsomes.
Microsomes are subcellular fractions containing membrane fragments.
This acylation reaction was rate limiting in brain microsomes.
The microsomes had no significant effect on tumor growth.
Mechanism of metabolic activation of chloroform by rat liver microsomes.
Rat hepatic microsomes are used as the enzyme source.
Stability of the compounds to human and mouse microsomes.
Human liver microsomes were obtained from a commercial source.
Similar results were obtained using human liver microsomes.
Microsomes are isolated from human or cynomolgus monkey tissue.
Metabolic stability in human hepatic microsomes.
Microsomes were then prepared in accordance with conventional methods.
See also
The metabolic stability was studied in human liver microsomes.
Rat hepatic microsomes were used as the source of the enzyme.
Cucurbitacin e is hydrolyzed to cucurbitacin i in plasma and in human liver microsomes.
Microsomes are small cell particles.
Metabolic stability in human liver microsomes of compounds of this invention.
Microsomes from control rats.
Obtaining the placental microsomes.
Therefore liver microsomes accelerate the decomposition of the compound.
Incubation in mouse liver microsomes.
Microsomes which are not incubated with substrate serve as reference.
The size of the protein was unaffected by the presence of microsomes.
Retinol esterification by microsomes from the mucosa of human small intestine.
They show good chemical stability in plasma and in microsomes.
The glucuronidation activity of liver microsomes was different between species.
The microsomes were recovered from the processing of hepatocytes with ultrasound.
No metabolism of avibactam was observed in human liver preparations microsomes and hepatocytes.
Glucuronidation in human liver microsomes like in rat liver microsomes is stereoselective.
Microsomes are isolated by homogenization with a polytron and several centrifugation steps.
The inactivation can be observed in postmitochondrial supernatant as well as in washed microsomes.
Human or rat liver microsomes incubations were conducted in duplicate in polypropylene tubes.
The membrane preparations used are rat central nervous system microsomes.
Rat liver microsomes.
Approximately equal concentrations were found in the smooth and rough microsomes.
Microsomes were prepared by homogenization of the tissue followed by differential centrifugation of the homogenate.
Covalent binding studies can be performed with hepatic microsomes or hepatocytes.
The stability test in liver microsomes was carried out in the following procedure.
Microsomes were obtained from the enterocytes as described for human liver microsomes.
The reaction was started by adding the microsomes and the substrate.
Lapatinib did not significantly inhibit the following enzymes in human liver microsomes.
Enzyme activities are measured using microsomes derived from human adrenal tissues.
Monoamine oxidase has been isolated and purified from bovine thyroid microsomes.
Microsomes can be concentrated and separated from other cellular debris by differential centrifugation.
An in vitro metabolic stability study using rat liver microsomes was then performed.
Hepatic microsomes were prepared from individual human livers by the process of differential centrifugation.
All incubations were performed as described under incubations with human liver microsomes.
