Examples of 'mitotane' in a sentence
Meaning of "mitotane"
mitotane: A medication used in the treatment of adrenal cortical carcinoma, a rare form of cancer that affects the adrenal glands. Mitotane works by inhibiting the production of hormones from the adrenal cortex
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- A particular oral drug used to treat cancer.
How to use "mitotane" in a sentence
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mitotane
Improvement after mitotane discontinuation has been observed.
Mitotane oily formulation and matrix were tested.
No proven antidotes have been established for mitotane overdose.
Mitotane is an inhibitor of the adrenal cortex.
Hepatotoxicity has been observed in patients treated with mitotane.
Mitotane has not been studied in a comprehensive clinical development program.
Solubility was determined by incremental loading of mitotane.
Mitotane tissue accumulation.
The active substance is mitotane.
Mitotane was given alone or combined with chemotherapy with various agents.
Lysodren is a medicine that contains the active substance mitotane.
The genotoxic and carcinogenic potential of mitotane has not been investigated.
Animal reproduction studies have not been conducted with mitotane.
The use of mitotane in patients with severe hepatic impairment is not recommended.
Reproductive toxicity studies have not been performed with mitotane.
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Caution should be exercised and frequent monitoring of mitotane plasma levels is highly recommended.
After six months mitotane plasma levels were undetectable and the patient recovered clinically.
Liver enzymes levels normalize when the mitotane dose is decreased.
Caution and close monitoring of mitotane plasma levels are highly recommended when treating overweight patients.
In dogs, treatment is accomplished with trilostane or with mitotane.
The full amount of Mitotane was added in a single portion.
Non-clinical data on the general toxicity of mitotane is limited.
Clinical efficacy Mitotane has not been studied in a comprehensive clinical development program.
Neuro-psychological retardation may be observed during mitotane treatment.
The prolonged elimination of mitotane from the body after discontinuation of Lysodren should be considered.
In children and adolescents, neuro-psychological retardation can be observed during mitotane treatment.
Because of its lipophilic nature, mitotane is not likely to be dialysable.
When mitotane is used, large doses of hydrocortisone or dexamethasone may be needed.
Self-microemulsifying mitotane composition.
The term ' mitotane oily formulation ' refers to a matrix in which mitotane has been incorporated.
Red blood cell, white blood cell and platelet counts should be monitored during mitotane treatment.
Data with various mitotane formulations suggest that administration with fat-rich food enhances absorption of mitotane.
Paediatric patients Neuro-psychological retardation may be observed during mitotane treatment.
If you are allergic ( hypersensitive ) to mitotane or any of the other ingredients of Lysodren.
Mitotane ( Lysodren ) may be recommended after surgery for people with a high risk of cancer recurrence.
Blood and lymphatic system disorders, All blood cells can be affected with mitotane treatment.
Mitotane is used to treat Cushing's Disease in dogs.
Paediatric patients, In children and adolescents, neuro-psychological retardation can be observed during mitotane treatment.
Mitotane apparently causes increased formation of 6-betahydroxy cholesterol.
Consequently, despite a constant dose, mitotane levels may increase.
Mitotane ( used to treat cancer of the adrenal glands ).
She had a follow-up as an outpatient and used mitotane 2 g per day.
Mitotane apparently causes increased formation of 6-beta - hydroxy cholesterol.
In addition, because of tissue accumulation, mitotane plasma levels should be monitored regularly e . g. monthly.
Mitotane can cause central nervous system undesirable effects at high concentrations see section 4.8.
Formulations numbered 1 to 4 were eventually set aside, as high mitotane loads could not be incorporated.
Monitoring of mitotane plasma levels is specially recommended in these patients see section 4.4.
Women of childbearing potential must use effective contraception during treatment with mitotane see section 4.6.
Weaker evidence has suggested that mitotane plasma levels above 14 mg / l may result in enhanced efficacy.
Leucopenia ( including neutropenia ), anemia and thrombocytopenia have been reported frequently during mitotane treatment see section 4.8.
