Examples of 'mitsunobu reaction' in a sentence
Meaning of "mitsunobu reaction"
Mitsunobu Reaction: a chemical reaction named after its discoverer, Oyo Mitsunobu, involving the conversion of alcohols into esters through the use of reagents like triphenylphosphine and diethyl azodicarboxylate
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- An organic reaction that converts an alcohol into a variety of functional groups, such as an ester, using triphenylphosphine and an azodicarboxylate.
How to use "mitsunobu reaction" in a sentence
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mitsunobu reaction
Mitsunobu reaction is performed in an appropriate solvent.
This ether link preferably is formed vía a Mitsunobu reaction.
Mitsunobu reaction has several applications in the synthesis of natural products and pharmaceuticals.
The chiral conversion is effected using a Mitsunobu reaction.
Preferably the Mitsunobu reaction mixture comprises toluene.
The reaction is analogous to the well known Mitsunobu reaction.
Then a Mitsunobu reaction with alcohol afforded the ether.
The reaction mechanism of the Mitsunobu reaction is fairly complex.
We find it convenient to perform a nucleophilc substitution reaction or a Mitsunobu reaction.
The reaction mechanism of the Mitsunobu reaction is a bit complex.
The Mitsunobu reaction can be carried out according to standard methods.
The reaction portrayed is a known in the art as a Mitsunobu reaction.
The Mitsunobu reaction yields the final products with inversion of configuration.
This reaction can be carried out by using the Mitsunobu reaction.
The use of thiols or amines in the Mitsunobu reaction can give additional derivatives.
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Variation on these conditions will be apparent from the literature on the Mitsunobu reaction.
The Mitsunobu reaction changes the stereochemical configuration at the carbon bearing the hydroxy group.
Silica gel chromatography is often required for the purification of coupling product of a Mitsunobu reaction.
A Mitsunobu reaction can be used to install the Cy group.
Another pathway involves the Mitsunobu reaction.
This Mitsunobu reaction was performed analogously to step vi in scheme XIII.
The preparation of amidates by means of the Mitsunobu reaction is described in J.
Mitsunobu reaction with hydroxyphthalimide gives Compound XXIX.
Ring substituent, stereochemistry and ring variations series were prepared by mitsunobu reaction.
However, the mitsunobu reaction suffers from many disadvantages.
Alternatively, it can be also achieved by carrying out Mitsunobu reaction.
Particularly, the Mitsunobu reaction is preferable.
Alternatively, alkylation of the benzaldehyde is carried out using a Mitsunobu reaction.
In this reaction, the Mitsunobu reaction can be employed.
The Mitsunobu reaction has been reviewed in the following references,.
Alkylation of the phenol vía Mitsunobu reaction with the desired alcohol gives 65.
Alternatively, the alkylation may be effected under typical Mitsunobu reaction conditions.
In addition, Mitsunobu reaction can also be used for alkylation of a phenolic hydroxyl group.
For alkylation of phenolic hydroxyl group, moreover, Mitsunobu reaction can be used.
The reaction is also performed by Mitsunobu reaction of Compound 7 using a known organic chemistry technique.
In some such embodiments, a phosphoryl azide provides the azide for the Mitsunobu reaction.
For the formation of an ether bond, Mitsunobu reaction described in a known literature Mitsunobu, et.
A Mitsunobu reaction is done to obtain the alpha-chloro compound from the corresponding alpha-hydroxy ester.
Scheme 1 exemplifies the introduction of a P2 substituent by way of a Mitsunobu reaction.
Now, the Mitsunobu Reaction in the latter method will be explained below.
Another method for the O-alkylation reaction is Mitsunobu reaction.
However, especially the Mitsunobu reaction can be a valuable reaction O.
X7 can be hydroxy which is activated in situ using the Mitsunobu reaction O.
Mitsunobu reaction between the intermediate 5 and bromophenol gave the ether 14.
Alcohols 6 are then reacted with substituted phenols 7 in a Mitsunobu reaction Chem.
A Mitsunobu reaction was then applied for introduction of the base moiety ( Figure 6 ).
Step 1 The general procedure for the Mitsunobu reaction was followed.
Mitsunobu reaction in presence of N-hydroxyphthalimide and deprotection with hydrazine leads to the desired compound 1093.
This reaction may be carried out by conventional procedures, for example using the Mitsunobu reaction O.
Mitsunobu reaction with I2a and ester saponification afforded the final compound from example 17.
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Examples of using Mitsunobu
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Mitsunobu conditions include those given above
This process is known in the art as a Mitsunobu coupling
Mitsunobu reaction is performed in an appropriate solvent
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It would give its reaction at a later date
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