Examples of 'modifying groups' in a sentence
Meaning of "modifying groups"
Modifying groups: Refers to adjusting or changing different sets of individuals or entities
How to use "modifying groups" in a sentence
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modifying groups
Exemplary modifying groups are discussed below.
Cholyl derivatives and analogues can also be used as modifying groups.
The hydrophilic modifying groups are not particularly limited.
The ratio of surface modification is largely dependent on the kind of modifying groups.
Nonionic hydrophilically modifying groups may likewise be present.
The modifying groups can be selected for one or more desirable property.
Controlling such chemical modifying groups in cells is also difficult.
Such modifying groups can also enhance the stability of the polymer.
This linker provides a method for attaching modifying groups to the oligonucleotide.
Additional modifying groups may be present on the polymer backbone.
The nucleic acid construct may also comprise various known modifying groups for nuclease resistance.
More preferred modifying groups those comprising a cholyl structure or an iminiobiotinyl group.
The EPO peptides of the invention comprise modifying groups such as PEG moieties.
Suitable modifying groups are described in subsection II below.
For example, small hydrophobic groups may be suitable modifying groups.
See also
Suitable types of modifying groups are described further in subsection II below.
In addition to cis-decalin containing groups . other polycyclic groups may be used as modifying groups.
Modifying Groups The peptide conjugates of the invention comprise a modifying group.
For example, hydrophobic groups and branched alkyl groups may be suitable modifying groups.
Modifying groups can be cyclic, heterocyclic or branched alkyl groups.
Examples of suitable N-terminal modifying groups are described further in subsection II below.
The modifying groups can be intercalators, groove-binding molecules, cationic amines and cationic polypeptides.
Examples of suitable N-terminal modifying groups are described funher in subsection II below.
The modifying groups can be selected from polymeric modifying groups such as, e.
The backbone, base, linkers and modifying groups can be added.
Other useful modifying groups include immunomodulating drugs, immunosuppressants, etc.
Glycosylation sites provide loci for conjugating modifying groups to the peptide, e . g ., by glycoconjugation.
Preferred modifying groups contains a cis-decalin group, such as a cholanoyl structure.
Exemplary polymeric modifying groups according to this embodiment include the moiety,.
For example, modifying groups derived from steroids or B-lactams may be suitable modifying groups.
Examples of suitable C-terminal modifying groups are described further in subsections II and III below.
Useful modifying groups include water-soluble polymers, therapeutic moieties, diagnostic moieties, biomolecules.
Accordingly, preferred modifying groups include a 1-piperidine acetyl group.
Preferred amino-terminal modifying groups include alkyl groups, e.g., methyl, ethyl, or isopropyl groups.
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