Examples of 'modulate the activity' in a sentence
Meaning of "modulate the activity"
modulate the activity: Adjust or regulate the intensity or frequency of a particular action or process
How to use "modulate the activity" in a sentence
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modulate the activity
Such agents may even modulate the activity of a further entity.
Ofparticular interest are monoclonal antibodies that neutralize or modulate the activity of the receptor.
Screening for agents that modulate the activity of cellular proliferation proteins may also be done.
The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor.
Pv-cells modulate the activity of principal cells with high temporal precision.
The invention relates to compounds that modulate the activity of neuroendocrine hormones.
It may also modulate the activity of various neurotransmitter receptors, including the Alpha-7 nicotinic receptor.
The resultant strain is further engineered to modulate the activity of pyruvate dehydrogenase.
As noted previously, these endogenous substances act on calcium channels to modulate the activity thereof.
A test substance able to modulate the activity may thereby be identified.
Furthermore, the object of the present invention is to modulate the activity of pDC.
A series of compounds which modulate the activity of PPA receptors has been found.
While the kinase activates the contractile system, caldesmon and calponin modulate the activity downward.
Transcranial stimulation allows us to modulate the activity of the cerebral cortex painlessly and safely.
The results demonstrate that Thiadiazolylpiperazine Compounds bind to and modulate the activity of mGluR5.
See also
Screening for agents that modulate the activity of ETR may also be done.
The results demonstrate Piperazine Compounds that bind to and modulate the activity of mGluR5.
Dopaminergic inputs from the VTA modulate the activity of GABAergic neurons within the nucleus accumbens.
These results indicate that ascorbate-induced lipid peroxidation can modulate the activity of FGF.
Plant sterols can also modulate the activity of membrane-bound enzymes.
Kits The invention provides various kits for detecting agents that modulate the activity of CCRL2.
The TIMPs typically modulate the activity of soluble, matrix bound and cell associated MMPs.
These same PTPases have also been shown to modulate the activity of certain RTKs.
They bind to and modulate the activity of a RUP3 receptor.
Phosphorylation is a post-translational ubiquitous ubiquitous and known to modulate the activity / action of many molecules o.
A compound described herein can modulate the activity of a molecular target ( e.g., a target protein methyltransferase ).
The invention further provides methods for identifying compounds that modulate the activity of a T-bet protein.
Preferred compounds act to modulate the activity of an " inhibitor of apoptosis protein " ( LAP ).
Other protein-binding molecules may also be employed to modulate the activity of GDF-8.
Methods for identifying compounds which modulate the activity of NAChRs are also provided.
Compounds The present invention provides compounds that modulate the activity of CCR ( 9 ).
Numerous related factors and cofactors modulate the activity of the biochemical pathway.
A compound of formula ( I ), or a pharmaceutically acceptable salt thereof, can modulate the activity of S1P receptors.
The compounds of the invention preferably modulate the activity of the protein kinase in vitro.
The truncated polypeptide is thus unable to properly modulate the activity of the second protein.
Such molecules can be used to modulate the activity of the LSR receptor.
Testing whether the candidate agent is able to modulate the activity of said polypeptide.
Alternatively, they may be used to modulate the activity of endogenous heparanase.
It comprises of a xanthine or a related compound to modulate the activity or expression of HDAC.
In particular, desirable compounds are those that modulate the activity of these polypeptides and polynucleotides.
The compounds are tested for the ability to modulate the activity of endothelin-1.
The compounds bind to and modulate the activity of a RUP3 receptor.
However, it appears that many of these peptides modulate the activity of ion channels.
Nicotinic PAMs could selectively modulate the activity of ACh at a7 NNRs.
Alternatively, the resultant strain may also be engineered to modulate the activity of lactate dehydrogenase.
Compounds of the invention can modulate the activity of S1P receptors.
The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase.
GSK-3 has been found to phosphorylate and modulate the activity of a number of regulatory proteins.
Therefore, the identification of effective small molecules to modulate the activity of HIF-2a is desirable.
A bioassay for identifying compounds which modulate the activity of human NMDA receptors, said bioassay comprising,.
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