Examples of 'monoclonals' in a sentence
Meaning of "monoclonals"
monoclonal (noun) - pertaining to or derived from a single clone of cells or organisms. This term is frequently used in biology and medicine, especially in the production of monoclonal antibodies for research and treatment purposes
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- plural of monoclonal
How to use "monoclonals" in a sentence
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monoclonals
Such monoclonals antibodies may also be humanised eg.
It may contain a mixture of a definite number of monoclonals.
Human monoclonals are likely to exhibit reduced or no immunogenicity in humans.
These are then used to make monoclonals.
Making monoclonals by hybridomas is well known.
One obtains neutralizing antibodies either by making monoclonals or by purchasing them.
The two monoclonals do not crossreact.
Most likely this is the case for the monoclonals as well.
Such monoclonals can be readily identified in cellular proliferation assays.
Further selection for positive monoclonals is done by limiting dilution cloning.
These monoclonals also inhibit the growth of the organism in culture.
It also is contemplated that a molecular cloning approach may be used to generate monoclonals.
The production in vitro of human monoclonals rarely results in high affinity antibodies.
Such monoclonals can be readily identified in specific binding member activity assays.
The inventors also contemplate the use of a molecular cloning approach to generate monoclonals.
See also
Further characterization of both monoclonals was performed with antibodies from mouse ascites.
Monoclonals antibodies are screened for binding to a protein from which the immunogen was derived.
This has been the approach to high affinity monoclonals intended for therapeutic use in humans.
Such monoclonals can be readily identified in activity assays for the weight modulators.
Hybridomas chosen for further studies were rendered monoclonals by repeated limiting dilution to ensure monoclonality.
Such monoclonals can be readily identified in BMP activity assays.
These scFv fragments were assembled from genes from monoclonals that had been previously isolated.
Improved monoclonals and recombinant proteins o Issues.
A polyclonal serum from the mouse used to generate monoclonals also stimulated thymidine uptake.
The monoclonals were purified and VZV glycoprotein specificity was analyzed by immunoprecipitation.
The data indicated that all tested monoclonals immunoreacted with PC antigen.
Such monoclonals can be readily identified in activity assays for the AIF.
In addition there have been limited reports of isolation of mouse monoclonals against TGFB.
Approximately eleven of the monoclonals were studied further after the first and second screens.
However, it is not necessary that these specific monoclonals be used.
Monoclonals that react with factor VIIa but not factor VII are selected.
We characterized antigens with which our Listeria specific monoclonals reacted by Western blot analysis.
The monoclonals recognized different epitopes of TRAP and enabled a sensitive assay thereof.
Similar modifications were often performed using other HRP conjugated monoclonals either individually or in combination.
The availability of these monoclonals provides a means for diagnosing Leptosphaeria infections in plant material.
On the other hand, the exact sequence recognized by the various monoclonals is not identical.
These monoclonals reacted with specific structures in CAV infected cells and not with uninfected cells.
Another important advantage of chimeric monoclonals is the increased serum half-life.
Monoclonals against toxin B were targeted to three domains of the protein.
Fc-epsilon receptor specific monoclonals can be constructed using conventional techniques.
Monoclonals showed poor reactivity with LHRH free acid and LHRH fragments containing free acid.
Preferred antibodies include monoclonal antibodies, including humanized, chimeric and human monoclonals or fragments thereof.
APRIL monoclonals of the invention detect APRIL in presence of serum.
The SIVcpz-ant isolate has the weakest reaction with the different monoclonals that even tested.
As a consequence, monoclonals of any specificity can be used.
FACS based assays for analysis of murine anti-human IgE monoclonals.
Other monoclonals in clinical development are zalutumumab, nimotuzumab, and matuzumab.
Consequently, we used these monoclonals to isolate CDX itself.
Monoclonals of both the IgG and IgM classes have been made, purified and characterized.
The peptides were tested for binding to the two Bet v 1 specific monoclonals.
