Examples of 'multiparticulates' in a sentence
Meaning of "multiparticulates"
Multiparticulates is an adjective used in pharmacology and pharmaceuticals to describe a drug delivery system composed of multiple particles or pellets. Multiparticulates are used to control drug release rates and improve bioavailability
How to use "multiparticulates" in a sentence
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multiparticulates
The multiparticulates may be packed into capsules.
A drug is usually present as active agent in the multiparticulates.
The multiparticulates can be further processed as a capsule or a tablet.
The droplets are congealed to form multiparticulates.
Multiparticulates are often used to provide sustained release of a drug.
This solid mass is then milled to form the multiparticulates.
The resultant multiparticulates can be employed as a fill in a capsule.
Melt extrusion of spherical multiparticulates.
The multiparticulates are obtainable by melt extrusion of an extrudable blend.
The strand is then cooled and divided to form multiparticulates.
The multiparticulates are preferably obtainable by extrusion of an extrudable blend.
Calcium pectinate capsules for encapsulation of bioadhesive multiparticulates are also available.
The matrix multiparticulates are then divided into unit doses.
This composition is then granulated to form multiparticulates of the desired size.
The multiparticulates are preferably formed into round beads or spheres.
See also
Additional optional excipients may also be included in the azithromycin multiparticulates.
Melt extruded multiparticulates comprising opioid analgesics are also known.
The retaining portions are each arranged to releasably retain a predetermined number of multiparticulates.
The multiparticulates of this invention can be used as a fill in a capsule.
Other additives may also be employed to produce multiparticulates within a set of predetermined specifications.
The multiparticulates were screened to remove oversized beads and fine material.
Sustained release can also be achieved by using multiparticulates coated with semipermeable membranes.
The multiparticulates of the invention comprise a plurality of particulates which are preferably spheroidal in shape.
Screw rotating speeds may play a part in the quality of the multiparticulates produced.
Another advantage of the multiparticulates is the improved stability of the drug.
The dosage form is designed to disintegrate rapidly in the stomach releasing the multiparticulates.
The active layererd multiparticulates are preheated and fluidized in a fluid bed processor.
This process contributes to the stability of the core of the multiparticulates of the invention.
Multiparticulates are small solid dosage forms which have many advantages over conventional tablets.
The extrudate may be cut into multiparticulates by any cutting means known in the art.
The Polymer coating solution is sprayed onto the tablets or multiparticulates.
The result is very irregularly shaped multiparticulates that are difficult to process into dosage forms.
Multiparticulates of the Invention.
Alternatively, the compositions may be administered as multiparticulates.
The obtained drug containing multiparticulates can be coated with additional functional layers and top coatings.
When a plurality of particulates is present, these are referred to as multiparticulates.
Drugs The multiparticulates formed by the process of the present invention comprise drug and a carrier.
The dissolution methods used for the encapsulated multiparticulates were as follows,.
The resulting multiparticulates may then be placed into a capsule along with the CETP inhibitor composition.
In yet another embodiment, the bazedoxifene is a coating applied to the multiparticulates.
Multiparticulates are preferably made by dry granulation ( including chilsonation ).
In an alternate embodiment, the multiparticulates are in the form of a non-disintegrating matrix.
The method of claim 2 further comprising compressing the multiparticulates into a tablet.
Spherical multiparticulates produced by this method offer a number of advantages,.
A coating was applied to the protective layered multiparticulates according to process described in example 5.
Several types of wet-granulation processes can be used to form tetracycline-containing multiparticulates.
The so-formed multiparticulates are then dried to remove any remaining liquid.
Pulsed-release formulations may be in the form of tablets or multiparticulates or a combination of both.
In one embodiment, the multiparticulates in a composition of the invention average 1 mm in diameter.
The method of claim 2 further comprising containing the multiparticulates within a gelatin capsule.
