Examples of 'muteins' in a sentence
Meaning of "muteins"
Muteins are proteins that have been genetically modified to have a muted function or activity
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- plural of mutein
How to use "muteins" in a sentence
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muteins
Other muteins of these hormones are also described.
These types of modified tICAM are referred to as muteins.
Such muteins are equivalents of the natural proteins.
The generation of albumin fusions containing albumin muteins.
Muteins within a group were analyzed on the same day.
Analogs include muteins of a polypeptide.
Muteins and analogs are included.
The same applies also to muteins and allelic variants.
Muteins of the natural polypeptide may be desirable in a variety of circumstances.
Further embodiments are directed to muteins.
All three muteins were biologically active.
Examples of such derivatives are muteins.
These muteins can be made and tested as described herein.
Characterization of the in vivo immunostimulatory activity of the muteins designed.
Muteins were diluted in medium and tested for biological activity.
See also
This method will produce recombinant muteins of this invention.
The bFGF muteins to be used for therapeutic administration must be sterile.
Measuring the therapeutic efficacy of the muteins in a murine model of transplantable tumors.
Muteins may be substantially homologous or substantially identical to the parent antibody.
Full length and truncated muteins in accordance with the invention.
Muteins having appropriate activity were confirmed in sequence using mass spectrometry analysis.
This method leads to the muteins according to the invention in recombinant form.
Methods for synthesizing conformationally and antigenically neutral muteins are also provided.
The cysteine muteins can be purified further by hydrophobic interaction chromatography.
These reaction conditions yielded monoPEGylated protein for all ten muteins.
Additional muteins with specific mutations are known and others will be developed.
These reaction conditions yielded monoPEGylated protein for all of the muteins.
Control experiments indicated that the muteins needed to be partially reduced to be PEGylated.
The muteins of hNGAL produced by genetic engineering can be purified by various proteinchemical methods.
The relatively low expression levels of these muteins makes it difficult to observe improved yields.
These muteins can be tested in animal disease models well known in the art.
Alternative resins can be used to capture hGH muteins from the osmotic shock mixture.
Synthesis of such muteins may be conveniently effected using conventional techniques and methods.
The following protocols were developed to refold insoluble hGH cysteine muteins into a biologically active form.
Eleven of the monoPEGylated muteins have been purified using the procedure described below.
The present disclosure also contemplates optimized variants of the lipocalin muteins specifically disclosed herein.
Proteins and muteins produced by deletions are within the purview of the present invention.
These types of modified ICAM are referred to as muteins.
Analogs can include various muteins of a sequence other than the naturally occurring peptide sequence.
Proteins expressed by such modified DNA are called muteins.
For inhalation the muteins of the invention can be first placed into a particulate dispersed form.
Summary of the Invention The invention provides a new class of EPO muteins.
Both human and rat muteins can be made using the expression systems of the invention.
Metastatic marker variants also include allelic variants, species variants, and muteins.
G Such inhibitors may also be muteins of the above constructs.
CLPI muteins are also within the scope of the invention.
The amino acid sequences of selected muteins are presented herein in the Sequence Listing.
Muteins so purified were assayed in the T and NK cell assays previously described.
Native Fc region polypeptides or muteins thereof may be employed in making these constructs.
Muteins of TFPI which retain the biological activity of TFPI are encompassed in this definition.
