Examples of 'n-glycan' in a sentence
Meaning of "n-glycan"
N-glycan is an adjective used in biochemistry to describe a type of glycan molecule that is linked to a protein via an N-glycosidic bond
How to use "n-glycan" in a sentence
Basic
Advanced
n-glycan
N-glycan maturation in plants is described by Gomord et al.
The instrument was calibrated using a mixed N-glycan standard.
A wide range of N-glycan structures can be present on lysosomal enzymes.
Another method featured oligosaccharide analysis of the N-glycan population.
The N-glycan may be attached to various positions in the glycoprotein.
Peak identities are resolved using commercially available N-glycan standards.
N-glycan analysis was done to the produced Trastuzumab antibodies as described above.
Further described herein is an N-glycan produced in the host cell is provided.
N-glycan patterns from Physcomitrella can be isolated and analysed as described by Koprivova et al.
In a more preferred embodiment, an N-glycan produced in the host cell is provided.
Further N-glycan elongation is carried out in a different manner in the two kingdoms.
In an example, the glycoprotein comprises naturally an N-glycan comprising an acceptor site.
The use of alternate N-glycan structures and free oligosaccharides described by Nothaft et al.
LEA has affinity for GaINAc indicating the presence of N-Glycan structures.
In one embodiment, N-glycan is attached to a site in the variable domain of the antibody.
See also
Shown here is the most abundant disialylated N-glycan present in such a spectrum.
In one embodiment, N-glycan core fucosylation of the glycoprotein is inhibited by a fucosylation inhibitor.
Fucose residues are found on different sites within the N-glycan tree so particularly,.
The N-glycan structure of the heavy chain of Rituxan ® was also analysed for comparison.
The microwave-assisted conditions were then extended to the synthesis of complex N-glycan mimics.
Different N-glycan branching and truncation of the N-terminus result in a characteristic pattern on isoelectric focusing.
Alternatively, sTNFR may be expressed in a system that incorporates GalNAc to the N-glycan moiety.
The total N-glycan profiles for these samples were obtained after enzymatic release of the N-glycans.
In certain alternative embodiments, the modification prevents formation of a mature N-glycan at the glycosylation site.
The pglB gene product transfers the N-glycan to a specific polypeptide acceptor site further described below.
For example the protein encoded by the sequence may add a terminal galactose during N-glycan maturation.
A first step in characterizing the N-glycan structures produced by PER.
The N-glycan pool of mammalian brain contains remarkably high levels of sialylated N-glycans.
Inverted triangles indicated N-glycan attachment points.
The N-glycan is preferably linked to Glcll in the lipid A core or a functional derivative thereof.
References and characteristics of putative proteins involved in the N-glycan biosynthesis in P. tricornutum.
These N-glycan precursors represent a trace amount of the total N - glycans present in the sample.
The results were confirmed with Campylobacter N-glycan specific immuneserum Fig.
The N-glycan site was obliterated at the DNA level by disrupting the N-glycan consensus sequence.
In one embodiment, the N-glycan comprises a terminal GalB residue.
A method according to any of Claims 1 to 6 wherein the glycan is a N-glycan.
By " precursor " N-glycan species is intended an N-glycan species that is incompletely processed.
Next, exoglycosidases were used to further investigate the N-glycan structures.
In one embodiment, the N-glycan is attached to the Fc domain of the antibody.
The method of claim 7, wherein the protein glycosylation is N-glycan sialylation.
In one embodiment, the N-glycan comprises one, two or more acceptor sites.
Mass spectra shown are the result of combining ≥ 50 individual scans per labeled N-glycan.
In one embodiment, the N-glycan has a structure according to the following formula,.
In particular, the anti-HIV antibodies provided bind to a complex-type N-glycan epitope of human HIV.
In one embodiment, the N-glycan comprises one, two or more terminal GalB residues.
Optionally, the glycan is an N-glycan.
C6 ™ produced N-glycan chains which contain Lewis x instead of Lewis y epitopes.
By an " immature precursor " glycosylation pattern, or N-glycan structure is meant a high mannose structure.
Tab.1, N-glycan structures of double knockout and tetra knockout Physcomitrella patens strains.
Inhibition of fucosylation was confirmed by N-glycan analysis as in Example 8.
