Examples of 'n-protecting group' in a sentence
Meaning of "n-protecting group"
n-protecting group - In chemistry, this phrase refers to a group that is used to protect a reactive site on a molecule from undergoing undesired reactions
How to use "n-protecting group" in a sentence
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n-protecting group
Is a suitable N-protecting group as known in the art.
Benzyl is an especially preferred N-protecting group.
The N-protecting group is as defined above.
After that a hydrogen atmosphere is generated to cleave the first N-protecting group.
Another means of removing that N-protecting group is by ozonolysis in ethyl acetate.
Any N-protecting group which is ordinarily used in peptide synthesis is available.
Deprotection to expose the amino-oxy functionality is performed on the peptide comprising an N-protecting group.
Removal of the N-protecting group by formic acid treatment leads to cyclization.
Following isolation of the product, the N-protecting group is removed.
Removal of the N-protecting group leads to enantiomerically highly enriched products.
The 3 ' - dimethyl group can optionally be protected with a conventional N-protecting group as set forth above.
Removal of the N-protecting group by hydrogenation of the intermediate leads to cyclization.
A compound of Formula La is prepared by removing the N-protecting group from compound 20.
Cleaving off the N-protecting group from compounds of formula to a compound of formula.
In formula ( 1 ) represents hydrogen atom or an N-protecting group.
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Removal of the N-protecting group then affords the desired metanicotine-type compound.
Compound ( I ) can be produced by removing N-protecting group PG from compound ( XXXI ).
Preferably the N-protecting group is Fmoc and preferably the tryptophan substituting group is Pmc.
Compound ( II ) can be produced by removing N-protecting group PG from compound ( XII ).
An N-protecting group may, for example, be an acetyl, tertbutoxycarbonyl or trichloroethyloxycarbonyl group.
In this case, specific examples of the N-protecting group include methoxymethyl, benzyl and trityl groups.
The N-protecting group ( carbamate, benzyl, sulfonyl, acetyl ) is finally removed in a conventional manner.
In another embodiment, the N-protecting group Rp is typically benzyl.
The N-protecting group ( carbamate, benzyl, sulphonyl, acetyl ) is finally removed in a conventional manner.
D Serine ( 1 ) is protected with a N-protecting group known in the art, by standard techniques.
The N-protecting group is removed from G-III to afford G-IV.
A preferred N-protecting group is benzyl.
An example of an N-protecting group easily removed with acid is t-butyloxycarbonyl ( BOC ).
Q is an N-protecting group.
Deprotection of the N-protecting group according to the conventional methods gives the expected compounds ( V ).
Further, examples of the N-protecting group include a benzyloxycarbonyl group and a dibenzyl group.
Removing the N-protecting group from the product thus obtained ;.
Examples of R ₁ ₀ when an N-protecting group include benzyl and substituted benzyl.
Removing the N-protecting group from the product obtained in step ( c ) ;.
Removing the N-protecting group from the product obtained in step ( a ) ;.
Removing the N-protecting group from the product obtained in step ( f ) ;.
A preferred N-protecting group is the t-butyloxycarbonyl ( BOC ) group.
In one embodiment, the N-protecting group Rp is typically tert-butoxycarbonyl ( BOC ).
It is preferred that the N-protecting group be t - butoxycarbonyl ( BOC ) or benzyloxycarbony ( CBZ ).
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