Examples of 'narrow therapeutic index' in a sentence
Meaning of "narrow therapeutic index"
Narrow therapeutic index: A term used in pharmacology to describe the small difference between the minimum effective dose and the minimum toxic dose of a medication. Medications with a narrow therapeutic index require careful monitoring to avoid adverse effects
How to use "narrow therapeutic index" in a sentence
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narrow therapeutic index
Fampridine has a narrow therapeutic index.
Use of ciprofloxacin is cautioned in patients on theophylline due to its narrow therapeutic index.
Warfarin has a narrow therapeutic index.
Risperidone is a highly potent drug having a relatively narrow therapeutic index.
The drugs with a narrow therapeutic index were identified in tertiary source of reference in pharmacotherapy.
Tobramycin is thus said to be a drug with a narrow therapeutic index.
Colchicine has a narrow therapeutic index and should be monitored, dose reduction if required.
Caution is advised when prescribing narrow therapeutic index drugs.
Examples of narrow therapeutic index drugs include theophylline, lithium carbonate, and digoxin.
This is particularly relevant for drugs with a narrow therapeutic index.
Dabigatran etexilate has a narrow therapeutic index and should be monitored, and dose reduction if required.
Existing full agonist compounds such as terlipressin have a narrow therapeutic index.
However, the CHMP took note of the narrow therapeutic index of dextropropoxyphen containing products.
Cyclosporin requires accurate dose measurement because of its narrow therapeutic index.
Co-administration of CYP substrates with narrow therapeutic index should therefore be made with caution.
See also
Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic index.
Cyclosporine is an immunosuppressant drug with a narrow therapeutic index and large variability in pharmacokinetics.
The composition of claim 1, wherein the pharmaceutically active ingredient comprises a drug with narrow therapeutic index.
This position can be used for drugs with a narrow therapeutic index for low level infusion.
However, the major problem with nearly all conventional chemotherapeutic agents is their narrow therapeutic index.
However, it has a narrow therapeutic index and is hepatotoxic dose-dependent.
Patients treated often suffered side effects due to the narrow therapeutic index of these products.
Critical dose drug ( e.g. Narrow therapeutic index drug ) or other clinical risk considerations.
In addition, letrozole is not considered to have a narrow therapeutic index.
CYP3A4 substrates with narrow therapeutic index.
While clonidine is a desirable potent analgesic drug, it has a narrow therapeutic index.
CYP2D6 substrates with narrow therapeutic index.
Such an increase might potentially be relevant for CYP2D6 substrates with narrow therapeutic index.
Monitoring plasma concentrations: Narrow therapeutic index.
Monitor P-gp substrate concentration for drugs with narrow therapeutic index.
Ciclosporin is considered a ‘ critical dose drug ' with narrow therapeutic index.
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