Examples of 'natural ligand' in a sentence
Meaning of "natural ligand"
natural ligand - In scientific contexts, it describes a molecule that binds to a receptor naturally, triggering a biological response
How to use "natural ligand" in a sentence
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natural ligand
At physiological concentrations pristanic acid is a natural ligand for PPARĪ±.
Specific natural ligand will then be identified and purified as above described.
Biological activity also included binding to its natural ligand.
Natural ligand sequences can be engineered to increase their specificity for a particular target cell.
The inhibitors were very effective at preventing binding of the natural ligand at low concentration.
A natural ligand may include MHC with or without a peptide presented.
Such antagonistic effects can be achieved by direct neutralization or binding of its natural ligand.
The Fc region of human IgG is the natural ligand for receptors on monocytic cells.
The cellular receptors for these proteins are classified based on the chemokine natural ligand.
It is believed that there may be natural ligand interacting with the PSM antigen.
The antibodies bind KDR at least as strongly as the natural ligand.
The natural ligand may be EGF.
The first molecule need not necessarily be the natural ligand of the second molecule.
The natural ligand of KDR is human VEGF.
These results suggest that the natural ligand for SLAM is SLAM itself.
See also
In a preferred embodiment, the agonist is other than a homolog of a natural ligand.
Receptor R and its natural ligand are proposed as a drug target.
The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand.
Osteoprotegerin is a secreted natural ligand of RANKL that can reduce the free serum RANKL concentration.
The protein called protein S is also a potential natural ligand of the TAM kinases.
The natural ligand APRIL is potentially useful as or as part of a BCMA-targeting therapeutic.
In parallel, attempts to identify the natural ligand of CupB6 were also carried out.
The natural ligand for SLAM should also provide such a co-stimulatory signal.
The cell-free system does not require the natural ligand or knowledge of its identity.
However, the natural ligand of the NKT cell receptor has not been previously identified.
The cell-free system does not required the natural ligand or knowledge of its identity.
Describe the OB-fold-protein domains for binding with their natural ligand.
Conclusion We purified EBI2 natural ligand from sheep liver obtained from a peritonitis sepsis model.
A preferred avB5 antagonist peptide corresponds in sequence to the natural ligand in the RGD-containing region.
With respect to PR, its natural ligand progesterone also cross-reacts with MR and GR.
An endogenous ligand is a ligand that is an endogenous, natural ligand for a native GPCR.
A natural ligand able to associate with the coreceptor ICAM-1 seems suitable.
The only receptor that does not have any known natural ligand is HER2.
In order to identify the natural ligand for SLAM, a SLAM-immunoglobulin fusiĆ³n protein ( SLAM-Ig ) was generated.
The 4-hydroxyl substitution was included to more closely mimic thyroxine, the natural ligand ofTTR.
Other mice received annexin V, a natural ligand that binds to anionic phospholipids.
They are activated by the neurotransmitter 5-HT, which is their natural ligand.
N-Acetyllactosamine is a better natural ligand to galectin-3 than galactose is.
The natural ligand of RXRs is 9 - cis - retinoic acid.
Figure 14a is a schematic illustration of a ligand-receptor interaction between a natural ligand and a natural receptor ;.
Figure 7, Purification of hEBI2 natural ligand from human septic liver extract, 5 step liquid chromatography procedure.
The EP4 receptor is a 7-transmembrane receptor and its natural ligand is the prostaglandin PGE2.
The natural ligand of the RXRs is 9-cis-retinoic acid.
It is antigenic and binds to GM-1 ganglioside, its natural ligand on the intestinal epithelia.
It was discovered as a natural ligand of the growth-hormone secretagogue receptor type 1a ( GHS-R ) Refs.
ATRA does not bind to RXR, for which 9-cis-retinoic acid is the natural ligand.
PGD2 is the natural ligand for CRTh2.
ATRA does not bind to RXR, for which 9 - cis - retinoic acid is the natural ligand.
CRM197 is a natural ligand of HB-EGF capable of blocking its binding to the EGFR.
Prostaglandin E2 ( PGE2 ) is a natural ligand for all sub-types of the EP receptor.
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