Examples of 'nebivolol' in a sentence
Meaning of "nebivolol"
Nebivolol is a noun referring to a medication used for the treatment of high blood pressure. It belongs to a class of drugs called beta-blockers
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- A β1 receptor blocker with nitric oxide-potentiating vasodilatory effect, used to treat hypertension.
How to use "nebivolol" in a sentence
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nebivolol
Nebivolol does not affect the speed of psychomotor reactions.
A process for preparation of racemic nebivolol.
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Process for the preparation of nebivolol.
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A new method for producing nebivolol hydrochloride of high purity.
Nebivolol can enhance the symptoms of peripheral circulatory disorders.
Literature reports several processes for the preparation of nebivolol.
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According to this invention the characteristics of the micronized nebivolol hydrochloride are as follows.
Nebivolol is useful in the treatment and prevention of coronary vascular disorders.
The preferred acid addition salt of nebivolol is the hydrochloride salt.
Nebivolol is available as a racemic mixture of d and l isomers with dual mechanism of action.
Other studies did not show relevant effects of the use of nebivolol and digoxin.
See also
Nebivolol is a beta blocker used to treat high blood pressure and heart failure.
This has an impact not only on the yield but also on quality of nebivolol.
Nebivolol is mainly used for the treatment and prevention of coronary vascular disorders.
After treatment with isopropylacetate racemic Nebivolol of high purity is obtained.
Often tablets Nebivolol prescribed as part of complex therapy.
With simultaneous use with sympathomimetics, the pharmacological activity of nebivolol is suppressed.
Processes for preparations of nebivolol and related compounds were described in EP Patent No.
Nebivolol is manufactured by Forest Laboratories.
The MAH has submitted a bioequivalence study for Nebivolol during the course of the reexamination.
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When applied simultaneously with sympathomimetics, the pharmacological activity of nebivolol is suppressed.
Nebivolol is represented by the following structure,.
Hence, the present invention provides a particularly advantageous formulation of nebivolol hydrochloride.
In vitro, nebivolol has no antioxidative effect.
For achieving appropriate dissolution rate or bioavailability of nebivolol hydrochloride, micronized nebivoiol is needed.
In the nebivolol treatment group, no significant changes in heart function were noted.
Compared with aspirin alone, addition of nebivolol to treatment improved brachial endothelial function.
Most effective process for base-free preparation of ketone intermediates usable for manufacture of nebivolol.
The daily dose of nebivolol can be administered in single dose o . d.
After this initial evaluation, we started the treatment with nebivolol in the intervention group.
Patients treated with nebivolol also showed improvement in HRR in the 1 and 2 minutes.
Deprotection General procedure for nebivolol deprotection,.
Example 9, racemic nebivolol free base General procedure was applied to dl benzyl Nebivolol free base.
Literature reports several processes for the preparation of nebivolol and / or of important synthesis intermediates.
Last nebivolol searches,.
Conraads et al . evaluated the therapy with nebivolol in HFNEF.
Qualitatively, the effect of the nebivolol hydroxy analogues and of vitamin E is similar.
Coupling reaction General procedure for benzyl nebivolol formation,.
Thus, the process of making racemic Nebivolol based on such strategy is complicated and inefficient.
Nebivolol contains four asymmetric centres, and therefore 16 stereoisomers are theoretically possible.
Figure 6 is a scheme demonstrating a process of making racemic Nebivolol and its pharmaceutically acceptable salts.
Nebivolol contains four asymmetric centers, and therefore 16 stereoisomers are theoretically possible.
The overall synthesis is illustrated in scheme 2, wherein racemic Nebivolol is depicted with the formula I.
The plasma levels of nebivolol were measured by using a validated LCMS / MS method.
Final deprotection by catalytical hydrogenation of b12 gave l - Nebivolol.
