Examples of 'negative regulator' in a sentence
Meaning of "negative regulator"
a type of protein or molecule that acts to inhibit or block a biological process or pathway
How to use "negative regulator" in a sentence
Basic
Advanced
negative regulator
The fur protein can act as a positive or negative regulator.
Negative regulator of transcription.
Sclerostin is a potent negative regulator of bone formation in men and mice.
An antisense or cosuppression construct would act as a dominant negative regulator of gene activity.
The gene pdhR is a negative regulator of the transcription of its operon.
Also disclosed herein is a method of identifying a positive or a negative regulator of osteoclast differentiation.
May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.
These results demonstrate that SIRPa is a negative regulator of tumor cell killing in vivo.
OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes.
It also functions as a negative regulator of the RAS.
It is a negative regulator of certain types of HEMATOPOIETIC STEM CELLS.
Neurofibromin is a negative regulator of Ras.
The negative regulator TACI also binds to both BAFF and APRIL.
The AraC protein is both a positive and negative regulator of PBAD.
A cell provided with a negative regulator of osteoclast differentiation may have a decreased level of differentiation.
See also
Therapeutic Uses Sclerostin functions as a negative regulator of bone formation.
PKA is a key negative regulator of lymphocyte function.
In this context, the hRR may be considered as a negative regulator of oncogenesis.
CFTR is also a negative regulator of the sodium channel ENaC.
Initially when DnaB binds to dnaA, it is associated with dnaC, a negative regulator.
We identified a negative regulator for the IMD pathway.
They showed phenotypes that clearly implicate Pga1 as an important negative regulator of conidiogenesis.
APC is a negative regulator of the Wnt signalling pathway.
The wild type MIO gene thus acts as a negative regulator of the pathogen response.
Also such negative regulator may, upon its inhibition, serve as a target to promote bone resorption.
In addition PCR for the putative negative regulator gene tcdC will be carried out.
According to the context, YY1 can act either as a positive regulator or as a negative regulator.
Studies have also suggested that Lyn is a negative regulator of apoptosis in various cell systems.
The pathway also probably involves FcYR ( in Monocytes / Macrophages and B cells ) as a negative regulator.
One GAP serves as a negative regulator of another GAP.
The tumor-suppressor phosphatase, PTEN, dephosphorylates PIP3 and therefore acts as a negative regulator of Akt activation.
PDHK functions as a negative regulator by inactivating PDH vÃa phosphorylation.
These surprising results show that ACE2 is a critical negative regulator of heart contractility.
GDF8 is a negative regulator of skeletal muscle mass.
Wnt Signaling Assay NOTUM can act as a negative regulator of Wnt signaling.
Follistatin (Fst), a negative regulator of TGFβ superfamily signalling, is an important inhibitor during embryonic development.
Our results suggest that Ikaros is a negative regulator of B cell activation.
GSK-3 is a negative regulator of the insulin-induced signal in this pathway.
For example, active myostatin is a negative regulator of skeletal muscle mass.
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation.
CCCTC-Binding factor or CTCF was initially discovered as a negative regulator of the chicken c-myc gene.
PD-1 is another negative regulator of adaptive immune response that is expressed on activated T-cells.
They also include agents which up-regulate a negative regulator of Hh signaling component.
CTLA-4, a negative regulator of autoimmune disease.
Furthermore, the human mitochondrial rhomboid protease PARL functions as a negative regulator of mitochondrial degradation.
PD-1 is a broad negative regulator of immune responses.
These results provided further show that BTK is a physiologically important negative regulator of Fas-mediated apoptosis.
The Neurofibromin 1 gene is a negative regulator of the Ras oncogene signal transduction pathway.
The design of a CD28/B7 inhibitor has exploited the endogenous negative regulator of this system, CTLA4.
Thus, CTLA4 is a critical negative regulator of T cell responses Waterhouse et al.
You'll also be interested in:
Examples of using Regulator
Show more
Turn the temperature regulator to a lower number
Regulator knob has continuous air leak
A damaged orifice or regulator which requires replacement
Examples of using Negative
Show more
Dissolution of etheric negative etheric or astral objects
Negative test results would also be recorded
Suitable for extended negative pressure service
