Examples of 'nf-kb activation' in a sentence
Meaning of "nf-kb activation"
nf-kb activation: Refers to the process by which the transcription factor NF-kB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) becomes active in regulating gene expression. It plays a critical role in immune responses, inflammation, cell proliferation, and apoptosis
How to use "nf-kb activation" in a sentence
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nf-kb activation
However, this enhancement of NF-kB activation was blocked by overexpression of dnNIK.
Luciferase reporter assay for NF-kB activation.
Compounds able to inhibit NF-kB activation are selected for future testing.
Recent publications have partially elucidated the NF-kB activation.
Another class of compounds known to inhibit NF-kB activation are anti-inflammatory corticosteroids.
Induction of glucocorticoid expression leads to upregulation of IkB and thereby blocks NF-kB activation.
In certain preferred embodiments, the NF-kB activation inhibitor is a proteasome inhibitor.
Showed that free radicals can directly or synergistically mediate an upregulation of Nf-kB activation.
In certain preferred embodiments, the NF-kB activation inhibitor is a ubiquitin pathway inhibitor.
The protective effects of CO were abrogated by inhibition of NF-kB activation.
In these cells TLR-dependent NF-kB activation can be easily measured after stimulation.
Overexpression of dnNIK together with NIK inhibited this NF-kB activation.
Figure 6 shows the effect of cYc on NF-kB activation induced by the NIKaly mutant.
NF-kB activation was measured indirectly by measuring the luciferase activity present in the cells.
To provide for an increase in the induction of NF-kB activation and cell survival.
See also
NF-kB activation in cells is induced by overexpressing NIK.
Recent studies of the mechanism of NF-kB activation have provided new targets for drug intervention.
Therefore inhibiting the interaction of cYc and NIK may bring to inhibition of NF-kB activation.
NIK also partakes in NF-kB activation as a consequence of viral infection.
Such ligands allow to bypass the TLR4 signalling pathway and lead to NF-kB activation.
One experimental way to induce NF-kB activation in cells is by overexpressing NIK.
Unexpectedly, 4-hexylresorcinol also resulted in a substantial reduction in NF-kB activation.
However, there is no direct evidence that NF-kB activation is necessary for atherosclerosis T.
Preferably, said modulation is an inhibition of NF-kB activation.
In certain preferred embodiments, the NF-kB activation inhibitor inhibits phosphorylation of IkB-a.
More specifically, a-MSH or its derivatives inhibited TNF-a induced NF-kB activation and binding.
Preferred NF-kB activation inhibitors inhibit NF-kB activation by the ubiquitin-proteasome pathway.
Under these conditions cYc inhibits NF-kB activation induced by NIK.
NF-kB activation was calculated as the fold-induction by TNF-a over unstimulated control samples.
Any HIV replication that would have resulted from such NF-kB activation is thus diminished.
All together, RANK-L induced NF-kB activation is important for formation of mature osteoclasts.
The effect of induction of SIVA2 on LIGHT-mediated NF-kB activation was studied.
Figure 17B presents the NF-kB activation stemming from the indicated agents.
Induction of the LTB receptor by its ligand, results in NF-kB activation.
The use according to claims 1-3 wherein the NF-kB activation inhibitor comprises a proteasome inhibitor.
The TLR2 induced activation measured is advantageously the NF-kB activation.
For detection of NF-kB activation the cell were treated with LPS for 10 min.
Proteasome inhibition has also been associated with inhibition of NF-kB activation and stabilization of p53 levels.
It also blocks NF-kB activation and lowers levels of inflammatory cytokines [ R ].
It is possible, under experimental conditions, to induce NF-kB activation by overexpressing NIK.
GAPDH regulates NF-kB activation through its binding to TRAF2 and leads to HIF-1a induction.
Proteasome inhibitors also block IkB-a degradation and NF-kB activation Palombella, et al.
And NF-kB activation.
Figure 4 shows the concentration-dependent effect of cYc on NIK induced NF-kB activation.
This inhibition results in blockade of NF-kB activation associated with pro-inflammatory responses . Definitions.
Induction of the lymphotoxin beta ( LTB ) receptor by its ligand results in NF-kB activation.
Thus, SIVA2 elevation suppresses TNF induced NF-kB activation in Ramos cells.
The reduction in COX-2 and NO synthase was attributed to an inhibition of NF-kB activation.
In contrast, Fas ligand is unable to induce NF-kb activation as per Figure 10a.
In still another further embodiment, the antagonist anti-CD40 antibody inhibits NF-kB activation.
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Push button activation also remains available
It was probably drawn in by the stargate activation at first
Storing several activation files on the server
