Examples of 'nintedanib' in a sentence
Meaning of "nintedanib"
nintedanib (adjective): a term used to describe a medication that has specific properties to inhibit certain biological processes within the body
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- A particular drug used as part of the treatment regimen for some types of non-small-cell lung cancer and for idiopathic pulmonary fibrosis.
How to use "nintedanib" in a sentence
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nintedanib
Exposure to nintedanib increased linearly with age.
Ofev contains the active substance nintedanib.
Nintedanib treatment may be resumed at a reduced dose.
Vargatef contains the active substance nintedanib.
Administration of nintedanib was also associated with elevations of bilirubin.
Hence it is recommended to take nintedanib after food.
Nintedanib might cause weight loss.
Genotoxicity studies indicated no mutagenic potential for nintedanib.
Nintedanib may affect the way your wounds heal.
There is no specific antidote or treatment for nintedanib overdose.
Nintedanib can be used in geriatric population without any dose modifications.
Vargatef capsules contain the active substance nintedanib.
Based on the mechanism of action nintedanib may impair wound healing.
Subjects may not be on both pirfenidone and nintedanib.
This ensures that a steady amount of nintedanib is maintained in your blood stream.
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Women should not become pregnant while taking nintedanib.
Nintedanib trough concentrations remained stable for more than one year.
The active substance is nintedanib.
The potential for interactions of nintedanib with hormonal contraceptives was not explored.
An inverse correlation between body weight and exposure to nintedanib was observed.
Compositions and methods of using nintedanib for improving glaucoma surgery success.
Nintedanib has not been tested in patients with moderate to severe impairment of liver function.
No dedicated studies investigating the effect of nintedanib on wound healing were performed.
As expected via its mechanism of action perforation might occur in patients treated with nintedanib.
There is no information on the excretion of nintedanib and its metabolites in human milk.
Single dose toxicity studies in rats and mice indicated a low acute toxic potential of nintedanib.
Certain medications like pirfenidone or nintedanib may slow the progression of the disease.
Use of Nintedanib for the treatment of lung fibrosis.
Current literature continues to suggest that nintedanib may have a role to play in lung cancer.
The active substance of Vargatef is nintedanib.
Nintedanib was also not a substrate of BCRP.
Only a minor extent of the biotransformation of nintedanib consisted of CYP pathways.
Nintedanib is being tested in several phase I to III clinical trials for cancer.
OS in NSCLC patients eligible for treatment with nintedanib.
Nintedanib follows at least bi-phasic disposition kinetics.
What Vargatef contains The active substance is nintedanib.
Co-administration with nintedanib should be carefully considered.
Nintedanib is contraindicated in patients with known hypersensitivity to nintedanib, peanut or soya.
However, no thorough QT-trial of nintedanib administered in combination with docetaxel was conducted.
In such cases, patients should be monitored closely for tolerability of nintedanib.
New oncology studies planned for nintedanib in the future, wherever clinically.
Researchers tested the system 's effectiveness with pirfenidone and nintedanib.
On the same date, nintedanib was also approved for use in the country.
Scientists evaluated the system 's efficiency with pirfenidone and nintedanib.
Nintedanib is an indolinone-derived drug that inhibits the process of blood vessel formation, or angiogenesis.
If severe diarrhea persists despite symptomatic treatment, discontinue treatment with nintedanib.
The most common adverse effects of nintedanib are gastrointestinal adverse effects, particularly diarrhea and nausea.
Logistic regression revealed a statistically significant association of the anti-angiogenic effect to nintedanib exposure.
In preclinical disease models of lung fibrosis nintedanib exerts potent anti-fibrotic and anti-inflammatory activity.
Nintedanib also significantly reduced the rate of lung function decline, improving patients ' ability to breathe.