Examples of 'nonsense mutation' in a sentence
Meaning of "nonsense mutation"
Nonsense mutation: A type of genetic mutation that results in a premature stop codon, leading to the production of a nonfunctional or truncated protein
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- A point mutation that generates either a premature stop codon, or a codon that does not specify any amino acid.
How to use "nonsense mutation" in a sentence
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nonsense mutation
Patients who do not have a nonsense mutation.
This nonsense mutation precludes synthesis of a functional protein.
The mutation may be a nonsense mutation.
A nonsense mutation is a point mutation that results in a premature stop codon.
A suppressible stop codon is sometimes referred to as a nonsense mutation.
A nonsense mutation is a genetic mutation that functions as a biological stop sign.
Another example of disruption is a nonsense mutation.
Nonsense mutation is a mutation which introduces a stop codon into the sequence.
The mutation can be a nonsense mutation.
This nonsense mutation results in termination of translation aminoterminal of the transmembrane domain.
A treatment for nonsense mutation.
For use as a medicament for the treatment of a disease caused by a nonsense mutation.
Patients who do not have a nonsense mutation should not receive ataluren.
A nonsense mutation in DNA results in a premature stop codon within an mRNA.
It is also called a nonsense mutation.
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The nonsense mutation was confirmed by cloning and sequencing PCR products derived from both alleles.
There is a need to provide new nonsense mutation suppressors that are good drug candidates.
And a mutation to for a stop code-on is called a nonsense mutation.
Presence of a nonsense mutation in the dystrophin gene ;.
XY sex reversal associated with a nonsense mutation in SRY.
Compounds described as nonsense mutation suppressors are certain aminoglycoside antibiotics, e . g.
For example, this can be achieved by introducing a missense or a nonsense mutation.
Presence of a nonsense mutation in one of the alleles of the cftr gene ;.
A combination according to embodiment 28 for use in the treatment of a disease caused by a nonsense mutation.
Nonsense mutation is called a point mutation, as there is a change in a single nucleotide base.
In one embodiment, it has been determined through pre-screening that the patient possesses a nonsense mutation.
Presence of a nonsense mutation in one of the alleles of the Or gene ;.
Other times, the new nucleotide will accidently end the protein short, known as a nonsense mutation.
Nonsense mutation Duchenne muscular dystrophy, and highlights strong safety profile.
Genetic tests are available to determine if a patient 's DMD is caused by a nonsense mutation.
The mdx mouse carries a nonsense mutation in exon 23.
Patient 4 is being characterized to completely lack ADAMTS-13 protein due to a homozygous nonsense mutation.
It is a nonsense mutation on Exon4.
In a particular embodiment, the mRNA decay results from a nonsense mutation of DNA.
It is estimated that a nonsense mutation is the cause of DMD in approximately 13 % of patients.
Examples of specific alleles of these genes that comprise a nonsense mutation are provided in Table 1.
Identification of a nonsense mutation in the HNF4a gene in a german family, the Dresden-11 pedigree.
In the video, Dr. Ellen Welch answers our questions about nonsense mutation and ataluren.
Arg854X nonsense mutation is found in many affected African or African-American infants.
In particular, compounds of formula I act as nonsense mutation suppressors on frequent PTCs, e . g.
A phase 3 efficacy and safety study of ataluren ( PTC124 ) in patients with nonsense mutation cystic fibrosis.
ELX-02 is a lead molecule-targeting nonsense mutation in rare diseases.
A phase 3 extension study of ataluren ( PTC124 ) in patients with nonsense mutation dystrophinopathy.
Right, ( B ) Pedigree of an NPHS1 family with an affected child having a nonsense mutation in exon 26.
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Examples of using Nonsense
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Put all this nonsense in their heads
We do not have time for this nonsense
All that nonsense with my driving license
Examples of using Mutation
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Such a peculiar mutation has never been on record
It looks like some kind of pigment mutation
Whether a mutation is naturally or artificially induced is irrelevant
