Examples of 'notch receptor' in a sentence
Meaning of "notch receptor"
notch receptor ~ a type of cell surface receptor that plays a critical role in cell development, differentiation, and communication. Notch receptors are involved in various signaling pathways and are essential for controlling gene expression and cell-to-cell interactions
How to use "notch receptor" in a sentence
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notch receptor
Notch receptor activation was determined by measuring luciferase activity.
These allogeneic cells were genetically modified so that they temporarily expressed a portion of notch receptor.
Notch receptor is a signaling molecule that functions in cell development and differentiation.
Delta is a ligand for the Notch receptor.
Antagonists of a Notch receptor may trigger cell death indirectly by inhibiting angiogenesis.
Additional in vitro assays to evaluate antibodies against a Notch receptor.
This fragment has a high affinity for a Notch receptor or a ligand of a Notch receptor.
The antagonist is an antibody that specifically recognizes an epitope of a Notch receptor.
The Notch receptor agonists and antibodies can be fused to a heterologous polypeptide sequence.
The mice are administered an antagonist to the Notch receptor to inhibit tumor growth.
This invention also encompasses bispecific antibodies that specifically recognize a Notch receptor.
The Notch receptor was first identified in Drosophila mutants.
In certain embodiments, an antagonist of a Notch receptor is proteinaceous.
The Notch receptor may be any protein that mediates Notch signaling.
In certaininstances, an antagonist of a Notch receptor is proteinaceous.
See also
Notch receptor antibody 59R5 inhibits tumor formation and growth in vivo.
In some embodiments, the antibody inhibits binding of a ligand to a Notch receptor.
In all animal models tested, mutations in the Notch receptor result in developmental abnormalities.
Alternatively, the factor may inhibit the biological activity of the Notch receptor.
In other instances, antagonists of a Notch receptor can trigger cell death indirectly by inhibiting angiogenesis.
These trans-interactions lead to a sequence of protease mediated cleavages of the Notch receptor.
In some embodiments, the antagonist is a Notch receptor protein fusion that specifically binds to a Notch.
In some instances, the at least one additional Notch receptor is Notch4.
Preferably, the Notch receptor may be Notch 1 or Notch 4 receptor, but is not limited thereto.
In a third embodiment of the above methods, the Notch receptor protein is Notch3 receptor protein.
The present invention provides isolated antibodies against a Notch receptor such as human Notch2 and / or Notch3.
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Receptor is not sensitive to the type of change
Is that why that receptor network existed
This receptor can exist in three conformations
Examples of using Notch
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Align the notch with cutting line
Notch and click the grid in place
The fluke has a notch in the middle
