Examples of 'nucleic acid binding' in a sentence
Meaning of "nucleic acid binding"
Nucleic acid binding: Refers to the process of molecules binding to nucleic acids, such as DNA or RNA, and is commonly used in the context of molecular biology and biochemistry
How to use "nucleic acid binding" in a sentence
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nucleic acid binding
High nucleic acid binding affinity.
The hnRNP proteins have distinct nucleic acid binding properties.
Nucleic acid binding domains can bind to nucleic acids through hybridization.
The use of protamine as a polycationic nucleic acid binding protein is especially effective.
A nucleic acid binding dye such as an intercalating dye also can be used.
As described above to allow lysis and nucleic acid binding to take place.
The nucleic acid binding agent may produce a detectable signal directly or indirectly.
Preferred solid phase support materials use a quaternary onium nucleic acid binding portion.
Optionally a nucleic acid binding solid phase and.
Different chemical structures can be used in the backbone of the nucleic acid binding compound.
Methods for detecting nucleic acid binding proteins include nuclease protection assays.
These conjugates will be useful for sensitive immunoassays and nucleic acid binding assays.
The nucleic acid binding partners are synthesized with a biotin attached to one end.
The zinc finger may thus represent the original nucleic acid binding protein.
Preferred nucleic acid binding compounds of the invention are those which are chemically synthesized.
See also
nucleic acid amplification
nucleic acid amplification reaction
nucleic acid can
nucleic acid construct
nucleic acid amplification reaction
nucleic acid can
nucleic acid construct
The probes were then treated with hybridization buffer to block nonspecific nucleic acid binding sites.
The nucleic acid binding compound of the present invention can have any length.
Extrusion before the addition of nucleic acid would reduce nucleic acid binding to lipid aggregates.
It is preferred that the nucleic acid binding portion binds selectively to the desired site.
This is especially possible using chemical methods for the synthesis of nucleic acid binding compounds.
The nucleic acid binding compound used in the present invention can have any length.
The present invention also contemplates using nucleic acid binding compounds in combination with other reagents.
The nucleic acid binding portion may be a DNA binding portion or an RNA binding portion.
The NASC polynucleotide composition is capable of associating with a nucleic acid binding protein.
Use of an isolated nucleic acid binding surface provides a reaction zone having a small surface área.
The NASC polynucleotide composition is capable of binding at least two nucleic acid binding proteins.
High affinity nucleic acid binding properties for applications requiring the analysis of nucleated cells.
Cocktails that detect DNA or RNA could consist of nucleic acid binding molecules.
Preferably, a nucleic acid binding membrane is used.
In some embodiments, the proteins are nucleic acid binding proteins.
In particular, nucleic acid binding peptides or proteins show good results.
Illustratively, the material has low nucleic acid binding capacity.
In this embodiment, a nucleic acid binding compound is selectively employed to treat contamination by microorganisms.
It also contains a β-domain fold common for nucleic acid binding proteins.
In a first group, the nucleic acid binding compound is used as a detectable probe.
In preferred embodiments, the scaffold is capable of binding a nucleic acid binding protein.
The use of non-natural nucleic acid binding partners is not disclosed or suggested.
Here too, the zinc finger domain is a putative nucleic acid binding sequence.
The use of non-natural nucleic acid binding partners is not disclosed or anticipated.
A method as claimed in claim 1 or claim 2 wherein the protein is a nucleic acid binding protein.
In this case, the nucleic acid binding compound will contain a detectable reporter group.
In one embodiment, the viral vector particle comprises the nucleic acid binding site.
In some embodiments, the nucleic acid binding proteins are double-stranded nucleic acid binding proteins.
In a further aspect, the invention provides detecting THAP-family nucleic acid binding activity.
In one embodiment, the nucleic acid binding compound is selected from the group comprising furocoumarins.
The method of claim 6, wherein the composition comprises at least one nucleic acid binding dye.
The double-stranded nucleic acid binding proteins in particular embodiments of the invention are preferably thermostable.
And a frangible linker covalently linking the nucleic acid binding moiety and the effector moiety,.
Typically, the nucleic acid binding portion and the modifying or chromatin inactivation portion are fused.
Recently, a new kind of non-natural nucleic acid binding compounds was described.
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