Examples of 'off-target' in a sentence
Meaning of "off-target"
Off-target refers to unintended consequences or effects that occur as a result of a particular action or intervention
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- Away from a target.
How to use "off-target" in a sentence
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off-target
Measuring the off-target effect of sisiRNA.
The crosshairs were completely off-target.
No apparent off-target activities were noted.
Seed modifications reduce off-target effects.
Such off-target inhibition could include toxicity.
Nobody complains about those off-target effects.
Reducing off-target effects does contribute substantially to safety.
A financing plan that remains far off-target.
Off-target drift from a herbicide application to a neighbouring crop.
These treatments resulted in minimal off-target effects.
List of off-target sites are ordered by median position of mutations.
This effect is also referred to as an off-target effect.
Any off-target movement will cause bleaching on susceptible plants.
Looks like they have an alternate route off-target.
Deliberately off-target shots were fired by both and neither was hurt.
See also
Another important parameter is the incidence of off-target mutations.
The negative consequences of off-target movement can be quite pronounced.
It now appears most of these analyses have been off-target.
Off-target binding to related molecules could have significant clinical effects.
Businesses without a plan can easily get off-target.
Only the off-target data are useful to correct the accuracy of firing.
Another area of concern is the potential of off-target cuts.
This model is being used to predict off-target movement of pesticides more scientifically.
This is a concrete commitment and so these accusations are decidedly off-target.
In an embodiment, a governing gRNA reduces off-target or other unwanted activity.
Deliberately off-target shots are fired by both and honour is satisfied without injury.
Clean plumbing to reduce contamination and avoid off-target application.
A total of seven potential off-target sites for three sgRNAs were analyzed.
Such engineered meganucleases exhibit an extremely low frequency of off-target cutting.
Late off-target products occurred in absence of the reverse-transcriptase in all samples.
Other mutations have been introduced that reduce off-target cleavage activity.
If the off-target areas change as a result of a change in ownership, the affected producing wells.
The human genome was searched in silico for potential off-target sites.
The risk of off-target effects is a consideration in the clinical use of genome-editing reagents.
Mice tolerated the treatment well without obvious off-target effects.
The method may reduce the off-target activity as measured by interferon gamma levels.
Accordingly, it is advantageous to reduce and eliminate any off-target gene silencing.
This may reduce the level of off-target cleavage activity in the target cell.
In some circumstances a white signal is indicated when a fencer has hit off-target.
As a result, an increasingly complete picture of the off-target activity of the enzyme is emerging.
Many soldiers tried to avoid being accused of letting a fugitive escape by deliberately shooting off-target.
Do not apply during a temperature inversion because off-target movement potential is high.
Off-target drift in calm conditions can occur hours after the spray event was completed.
These metabolites are not expected to have antiviral activity or off-target pharmacologic activity.
Importantly, the question of off-target toxicity produced by the two systems has not been evaluated.
The compositions of the invention arrive at minimized off-target modifications when used.
Another way to minimize such off-target effects is to screen the siRNA for target specificity.
Another desirable goal is to discover a drug that exhibits minimal off-target inhibition.
The cleavage efficiency at each off-target sequence is predicted using an experimentally-derived weighting scheme.
In an embodiment of the disclosure, a governing gRNA reduces off-target or other unwanted activity.
