Examples of 'olaparib' in a sentence
Meaning of "olaparib"
olaparib (adjective) - relating to or containing olaparib, which is a medication used in the treatment of certain cancers. For instance, The patient was prescribed olaparib therapy for her ovarian cancer
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- A particular anticancer drug.
How to use "olaparib" in a sentence
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olaparib
Olaparib does not affect the pharmacokinetics of tamoxifen.
Lynparza contains the active substance olaparib.
Olaparib tablets and capsules are not interchangeable.
There is limited experience of overdose with olaparib.
Effect of olaparib on other medicinal products.
Carcinogenicity studies have not been conducted with olaparib.
Olaparib is available as a tablet and as a capsule.
Effect of olaparib on other drugs.
There are no animal studies on the excretion of olaparib in breast milk.
Retreatment with olaparib was not permitted following progression on olaparib.
The active substance is olaparib.
It is unknown whether olaparib or its metabolites are excreted in human milk.
Lynparza hard capsules contain the active substance olaparib.
The metabolism of olaparib is extensive.
Lynparza is also known as olaparib.
See also
Combination of olaparib with vaccines or immunosuppressant agents has not been studied.
It is also not recommended to consume grapefruit juice while on olaparib therapy.
It is not known whether olaparib or its metabolites are found in seminal fluid.
Olaparib capsules must not be used as a substitute for olaparib tablets.
No studies have been conducted to investigate the pharmacokinetics of olaparib in paediatric patients.
Ovarian cancer drug olaparib was approved in Scotland as new treatment.
The effect of hepatic impairment on exposure to olaparib has not been studied.
Olaparib targets mutations that change the way DNA is repaired.
How to access olaparib.
Olaparib works by targeting mutations that change the way DNA is repaired.
Dotted lines indicate the calculated cell survivals if additivity between AsiDNA and olaparib.
Patients could not have received prior olaparib or other PARP inhibitor treatment.
The PARP inhibitor shown to be active against endometrial cancer is olaparib.
Olaparib targets cancer cells that are not able to properly repair their DNA.
Demographic and baseline characteristics were generally well balanced between the olaparib and placebo arms.
Olaparib is a PARP inhibitor.
What Lynparza contains The active substance is olaparib.
No olaparib or placebo-treated patients discontinued due to diarrhoea.
Overall survival at one year following treatment with olaparib was,.
Olaparib showed no mutagenic potential, but was clastogenic in mammalian cells in vitro.
In particular, caution should be exercised if olaparib is administered in combination with any statin.
Olaparib shows success in tumor response rate for patients with BRCA-related cancers.
An exposure-response relationship between olaparib and decreases in haemoglobin has been demonstrated.
Any previous treatment with a PARP inhibitor, including olaparib.
DNA-damaging agents olaparib and cisplatin were applied to cells for 3 days.
From this cell model, a new predictive pattern of susceptibility to Olaparib was determined.
Olaparib is a type of cancer medicine called a PARP ( poly [ adenosine diphosphate-ribose ] polymerase ) inhibitor.
The health-related quality of life also got better in individuals of the Olaparib group.
Olaparib inhibited UGT1A1 in vitro, however, PBPK simulations suggest this is not of clinical importance.
The majority of patients remained on the 400 mg bd starting dose of olaparib.
Olaparib inhibits CYP3A4 in vitro and is predicted to be a mild CYP3A inhibitor in vivo.
Mice were imaged at baseline, or 30 minutes after IP injection of olaparib or iniparib.
Adding PARP inhibitors, either Olaparib or Veliparib, increased significantly the cell death ( full lines ).
CYP3A4/5 are the isozymes predominantly responsible for the metabolic clearance of olaparib.
Seven male patients were randomised ( 5 olaparib and 2 comparator ).
