Examples of 'olopatadine' in a sentence
Meaning of "olopatadine"
olopatadine (noun): A type of antihistamine medication often used to relieve symptoms of allergic conjunctivitis
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- A particular antihistamine used in eye drops to treat allergic conjunctivitis.
How to use "olopatadine" in a sentence
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olopatadine
Process for obtaining olopatadine and intermediates.
Olopatadine formulations for topical nasal administration.
A sprayer having a formulation comprising olopatadine is provided.
Olopatadine has a low order of acute toxicity in animals.
High concentration olopatadine ophthalmic composition.
Process for the preparation of olopatadine.
Olopatadine eye drops are not recommended for this age group.
The active substance is olopatadine.
Solubilizing high concentrations of olopatadine in a stable manner has proven difficult by itself.
Subsequent palladium catalyzed cyclization and deprotection provide olopatadine.
One polymer for aiding in solubilizing the olopatadine is polyvinylpyrrolidone.
Literature reports some alternative processes for the preparation of olopatadine.
The aqueous solubility of olopatadine HCl decreases with increasing concentration of NaCl.
The ophthalmic composition includes a relatively high concentration of olopatadine solubilized in aqueous solution.
Olopatadine is not recommended during pregnancy and in women of childbearing potential not using contraception.
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Solubilizing such higher concentrations of olopatadine has proven difficult.
The present invention relates to an ophthalmic composition containing a relatively high concentration of olopatadine.
Olopatadine hydrochloride bromide free of crystalline form A and pharmaceutically acceptable grade is thus obtained.
The application reports several processes for the preparation of olopatadine and analogues thereof.
Olopatadine is absorbed systemically, as are other topically administered medicinal products.
B Initial observations were performed prior to addition of excess olopatadine HCl.
Olopatadine is the cis form of the compound having the formula,.
NaCl caused a significant reduction in the rate of dissolution of olopatadine.
One ml of solution contains 1 mg olopatadine as hydrochloride.
Thus, innovation is required to solubilize a sufficient concentration of olopatadine.
Each mL of solution contains 1mg of olopatadine as hydrochloride.
Generally, olopatadine will be added in the form of a pharmaceutically acceptable salt.
Anti-allergic agents include olopatadine and epinastine.
Olopatadine nasal spray for use in a method of administering the spray, comprising,.
Figure 5 shows the buffer capacity of an olopatadine nasal spray composition.
Opatanol is a clear eye drop solution, which contains the active substance olopatadine.
Process for preparing olopatadine and / or a pharmaceutically acceptable salt thereof.
Among the main drugs of this group are ketotifen, epinastine, and olopatadine and alcaftadine.
The olopatadine butyl ester thus obtained has the following NMR spectrum,.
In all four cases, the NaCl was added after olopatadine during the compounding.
The ophthalmic or otic composition of claim 6 wherein the anti-allergic agent is pemirolast or olopatadine.
PATANOL ® brand of olopatadine hydrochloride ophthalmic solution is marketed as a topical anti-allergy composition.
The composition will include a Y-cyclodextrin derivative to aid in solubilizing the olopatadine.
Olopatadine is a known compound that can be obtained by the methods disclosed in U. S.
The composition will include polyvinylpyrrolidone ( PVP ) to aid in the solubilization of the olopatadine.
The active substance is olopatadine 1 mg / ml as hydrochloride.
What Opatanol contains - The active substance is olopatadine.
Olopatadine is a known anti-allergy drug.
Notably, PEG and HPMC are also believed to be aiding in the solubility of olopatadine.
An olopatadine pharmaceutical product, comprising,.
With addition of Na2HPO4, however, the dissolution of olopatadine was dramatically improved.
Olopatadine free-base can be conveniently re-crystallised with about 4 volumes of dimethylformamide.
At a pH higher than pKa2, anionic olopatadine ( with ionized carboxylic group ) is dominant.
Opatanol nasal spray is a solution containing 6 mg / ml of the active substance, olopatadine ( as the hydrochloride ).
At a pH lower than pKa1, cationic olopatadine ( with ionized tertiary amino group ) is dominant.
