Examples of 'osimertinib' in a sentence
Meaning of "osimertinib"
Osimertinib (noun): A medication used in the treatment of non-small cell lung cancer
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- A drug used to treat non-small-cell lung carcinomas with a specific mutation.
How to use "osimertinib" in a sentence
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osimertinib
Osimertinib is eliminated mainly via the liver.
The active substance is osimertinib as mesylate.
Carcinogenicity studies have not been performed with osimertinib.
The main metabolic pathway of osimertinib was oxidation and dealkylation.
It contains the active substance osimertinib.
Drink the osimertinib and water mixture right away.
Effect of gastric acid reducing active substances on osimertinib.
Osimertinib is an effective anticancer drug that works in this way.
Active substances that may increase osimertinib plasma concentrations.
Duration of response was more than twofold higher with osimertinib.
Active substances that may decrease osimertinib plasma concentrations.
Osimertinib did not cause genetic damage in in vitro and in vivo assays.
Substance osimertinib mesylate.
Osimertinib pharmacokinetic parameters have been characterized in healthy subjects and NSCLC patients.
There is insufficient information on the excretion of osimertinib or its metabolites in animal milk.
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The hepatic impairment marker serum albumin showed an effect on the PK of osimertinib.
It is not known whether osimertinib or its metabolites are excreted in human milk.
Based on studies in animals, female fertility may be impaired by treatment with osimertinib.
Molecular models of the lung cancer drug osimertinib in complex with EGFR.
Osimertinib may increase the exposure of BCRP substrates.
You are allergic ( hypersensitive ) to osimertinib or any of the other ingredients of this medicine.
Osimertinib penetrated the intact blood-brain barrier of the cynomolgus monkey i . v.
Based on in vitro data, osimertinib is an inhibitor of BCRP and.
Osimertinib may also be used as initial treatment for EGFR+ lung cancer.
Based on in vitro studies, osimertinib is a competitive inhibitor of BCRP transporters.
Strong CYP3A4 inducers can decrease the exposure of osimertinib.
Place your dose of osimertinib in a container that contains 2 ounces of water.
Therefore, CYP3A4 inhibitors are not likely to affect the exposure of osimertinib.
The recommended dose is 80 mg osimertinib once a day until disease progression or unacceptable toxicity.
TAGRISSO 40 mg tablets osimertinib.
By blocking EGFR, osimertinib helps to reduce the growth and spread of the cancer.
Each tablet contains 40 mg osimertinib as mesylate.
Osimertinib may increase the exposure of breast cancer resistant protein ( BCRP ) and P-glycoprotein ( P-gp ) substrates.
In vitro studies indicate that osimertinib is metabolized predominantly by CYP3A4, and CYP3A5.
Effects of osimertinib on P-gp and BCRP.
In vitro studies have shown that osimertinib is not a substrate of OATP1B1 and OATP1B3.
