Examples of 'oxindole' in a sentence
Meaning of "oxindole"
oxindole (noun): A chemical compound containing both an oxazole and an indole ring structure. Oxindoles are commonly found in natural products and pharmaceutical compounds, and they exhibit diverse biological activities
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- A bicyclic aromatic heterocycle containing a benzene ring fused with five-membered cyclic amide
- Any derivative of this compound
How to use "oxindole" in a sentence
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oxindole
Oxindole is an aromatic heterocyclic organic compound.
The starting material oxindole is known in the literature.
Indigo can be converted to isatin and then to oxindole.
Tetracyclic oxindole alkaloids act as antagonists.
General procedure for condensation of oxindole and aldehyde.
Alkylation of the oxindole appears to proceed by conventional mechanisms.
The insoluble part containing the starting oxindole was kept.
Particularly oxindole alkaloids stimulate leucocytes and macrophages in response to pathogens.
The TLC plate showed only a trace of the starting oxindole was present.
The oxindole derivative of the present invention encompasses both types of isomers.
The stereoselective synthesis of the alkylated oxindole 2a or 2b is an exothermic reaction.
The oxindole can be converted to an enantiomeric mixture using an achiral phase transfer catalyst.
Finally, we developed an original methodology for the synthesis of oxindole derivatives.
A common characteristic of the oxindole carboxamides of this invention is their acidic nature.
There have been several reports on its constituents, in particular, oxindole alkaloids.
See also
A number of oxindole alkaloids have already been isolated from the inner bark of this plant.
Thus, this study aimed to evaluate the relevance of oxindole alkaloids at u . tomen.
The oxindole is elaborated by a modification of the procedure of Gassman et.
Work-up of the extract and purification of the oxindole product is by standard methods.
As noted above, oxindole can be detected by standard analytical techniques.
It has been found that alkylation of the racemic mixture of oxindole 1 proceeds very rapidly.
The oxindole 1 and the catalyst are dissolved in an aromatic hydrocarbon solvent.
The active ingredients of the present invention, oxindole derivatives, partially comprise known compounds.
Slow addition of the alkylating agent improves selectivity for the predominating alkylated oxindole 2a or 2b.
The oxindole is elaborated by a modification of the procedure of Gassman et . al . J.
As the concentration of base decreases, the selectively for one of the alkylated oxindole decreases.
The oxindole 1 is a racemic mixture.
In one embodiment, the glucuronide moiety is attached through the N atom in the oxindole ring.
Oxindole derivative ( 1 ) produced according to the above methods may be mixture of isomers.
Most preferred are compounds of Formula IIa wherein or R6 and R7 form together an oxindole ring.
This reaction normally produces the oxindole derivative ( 9 ) mainly.
Oxindole 1 of Fischer as referenced in column 2.
The product from the acid-catalyzed rearrangement of 8 is assigned the oxindole structure 12.
Use of an oxindole derivative represented by the following formula ( I ) or a salt thereof,.
Cat 's claw 's bark and roots provide most of its immune-boosting qualities via oxindole alkaloids.
Of the oxindole derivatives of formula ( 1 ), preferred ones are those described below.
Simple oxidants such as N-bromosuccinimide will selectively oxidize indole 1 to oxindole 4 and 5.
The R3 substituent is linked to position 5 in the oxindole ring.
R3 is preferably linked at position 5 of the oxindole ring ;.
The R3 substituent is preferably in the 5-position of the oxindole ring ( d ).
