Examples of 'parent antibody' in a sentence
Meaning of "parent antibody"
parent antibody ~ an antibody produced by a parent cell that plays a role in the immune response
How to use "parent antibody" in a sentence
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parent antibody
Preferably said parent antibody is a diagnostic antibody.
In an other embodiment the tracer antibody is the parent antibody.
Preferably said parent antibody is a therapeutic antibody.
In one embodiment the capture antibody is the parent antibody.
The parent antibody need not be naturally occurring.
Muteins may be substantially homologous or substantially identical to the parent antibody.
The parent antibody is directed against a target antigen of interest.
Especially preferred said capture or said tracer antibody is said parent antibody.
Preferably the parent antibody is a humanized antibody or a human antibody.
Preferably said capture antibody or said tracer antibody is said parent antibody.
Preferably said parent antibody is a therapeutic antibody or a diagnostic antibody.
The modified oligosaccharides of the full length parent antibody may be hybrid or complex.
The parent antibody may comprise a native or wild type sequence.
Immunization of the animal is performed preferably with the parent antibody or fragments thereof.
Generally, a parent antibody may be a humanized or human antibody.
See also
Such functional variants typically retain significant sequence identity to the parent antibody.
The ADCC activity of the parent antibody was barely above background level.
Antibodies are defined herein as retaining at least one desired activity of the parent antibody.
Preferably the parent antibody is a chimeric, humanized or human antibody.
Affinity matured modular antibodies may exhibit a several logfold greater affinity than a parent antibody.
For example, the parent antibody may be a humanized or a human antibody.
Where a variant is to be generated, the parent antibody is prepared.
For example, the parent antibody may be a caninized or canine antibody.
In one embodiment of the invention, the parent antibody is of mouse origin.
Preferably the parent antibody is a chimeric antibody, humanized antibody, or human antibody.
The IgG1 antibody is nearly as avid as the mouse parent antibody.
As yet another example, the parent antibody is a murine monoclonal antibody.
The mutated antibodies are more potent than the non-mutated parent antibody.
Especially preferred is said parent antibody a therapeutic chimeric, humanized, or human antibody.
Anti-alpha toxin antibodies and fragments may be variants of the parent antibody.
The composition of claim 2 wherein the parent antibody or antibody fragment additionally comprises.
Functionally active variants may be obtained by changing the sequence of a parent antibody format, e . g.
Alternatively the tracer parent antibody is conjugated to an electrochemiluminescent label, like a ruthenium bispyridyl complex.
In one embodiment, an antibody derivative possesses a similar or identical function as the parent antibody.
Said monospecific bivalent parent antibody under a may be a human antibody, preferably, a recombinant human antibody.
This back-mutation criterion enables one to recover the activity of the parent antibody compound.
The parent antibody may have a murine framework, but preferably has a human framework region.
Said reference immunoglobulin is not specifically binding said anti-idiotype antibody and said parent antibody.
The parent antibody may have pre-existing strong binding affinity for the target antigen.
We injected the sFab construct and the control parent antibody mAb31 weekly for three months.
Variable regions An anti-alpha toxin antibody or fragment may prepared from a parent antibody.
The parent antibody may be a murine, chimeric, humanized or human antibody.
Summary list of test Fc-containing proteins preparations used herein Parent antibody Specific variant.
The parent antibody may be a native antibody or may already be a variant, e.g., a chimeric antibody.
Preferably, the substitution ( s ) are in the heavy chain variable domain of the parent antibody.
A parent antibody may be directed against a target antigen of interest, e.g. a biologically important polypeptide.
Such variants necessarily have less than 100 % sequence identity or similarity with the parent antibody.
Preferably said anti-parent-antibody antibody is an anti-idiotype antibody against said parent antibody.
Such molecules have less than 100 % sequence identity with the parent antibody or parent fusión polypeptide.
For example, a parent antibody has a human framework region and has human antibody constant region ( s ).
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Antibody status should be monitored and reported
The kinetics of antibody decline are also similar
Antibody persistence after booster immunisation adults
Examples of using Parent
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And his estimable parent rest in peace
Second parent adoption is also not possible
The antenna of the parent unit is fixed
