Examples of 'parent drug' in a sentence
Meaning of "parent drug"
parent drug: In pharmacology, a parent drug is the original form of a drug before it is metabolized into different substances in the body. It is usually the primary form of the medication that is administered
How to use "parent drug" in a sentence
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parent drug
Parent drug and half of its activity.
Pharmacological activity resides in the parent drug.
Metabolites and parent drug are excreted in the bile.
The tetrabutylammonium salt of the parent drug.
Unchanged parent drug is the predominant component in plasma.
Tretinoin activity is primarily due to the parent drug.
Traces of unchanged parent drug are found in urine and feces.
These metabolites are more potent than the parent drug.
The name of the parent drug is presented above each formula.
Most of the systemic exposure was from the parent drug.
Metabolism as well as biliary excretion of parent drug contribute to the elimination of paritaprevir.
Quetiapine fumarate activity is primarily due to the parent drug.
Also the formation of the parent drug was determined.
The activity of quetiapine is primarily due to the parent drug.
Whole blood was analyzed for parent drug and metabolites.
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Pibrentasvir was not metabolized and was recovered in feces only as unchanged parent drug.
Biliary excretion of parent drug was the major route of elimination for voxilaprevir.
A good prodrug should go back to the parent drug in plasma.
The parent drug is detected in higher concentrations than its metabolites in these matrices.
A good prodrug should go back to its parent drug in plasma.
Plasma samples were assayed for parent drug concentrations using an appropriate analytical method.
A good prodrug should change back to the parent drug easily.
Quantitation of intracellular parent drug and metabolic derivatives were conducted by HPLC.
Vismodegib is slowly eliminated by a combination of metabolism and excretion of parent drug substance.
Zonisamide is excreted primarily in urine as parent drug and as the glucuronide of a metabolite.
Trandolaprilat has about eight times the activity of its parent drug.
Pharmacokinetic parameters should be determined for the parent drug and important active or toxic metabolites.
Determination of comparative bioavailability should be based on data for the parent drug.
Parent drug and SMAP can additionally be glucuronidated.
Prodrugs may be easier to administer than the parent drug in some situations.
Prodrugs are designed to overcome various pharmaceutical or biopharmaceutical problems associated with the parent drug.
AU substances belonging Parent drug to the sulfonamide group.
A prodrug refers to an agent that is converted into the parent drug in vivo.
Parent drug and active metabolites, if present.
Prodrugs are typically useful for facilitating the administration of the parent drug.
Renal excretion of the parent drug is less than 4.
Such prodrugs forms may be converted into a pharmacologically active parent drug in vivo.
Further, the parent drug may be converted to a number of metabolites.
Generally the reference pH is the pH at which the parent drug is fully protonated.
In water, the parent drug is sparingly soluble and the solution is colorless.
The metabolic products are often less active than the parent drug or inactive.
Third, in some cases, the parent drug is poorly phosphhorylated in the target cells.
The lipophilicity of the compounds was substantially higher than that of the parent drug.
The tertiary amine-containing parent drug may be asenapine or olanzapine.
Norbuprenorphine appears to be excreted principally in urine at a slower rate than the parent drug.
The prodrug is converted to the parent drug chemically or by specific enzyme ( s ).
The functional group may be cleaved in vivo to release the active parent drug compound.
In rabbits, pegaptanib is eliminated as parent drug and metabolites primarily in the urine.
All double spacer containing paclitaxel prodrugs were converted to yield the corresponding parent drug.
Demonstration of the controlled release of parent drug from " activated " prodrugs.
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And his estimable parent rest in peace
Second parent adoption is also not possible
The antenna of the parent unit is fixed
