Examples of 'paroxetine hydrochloride' in a sentence
Meaning of "paroxetine hydrochloride"
Paroxetine hydrochloride: This phrase denotes a specific pharmaceutical compound that is commonly used as an antidepressant medication. It is a selective serotonin reuptake inhibitor (SSRI) that is prescribed to treat depression, anxiety disorders, and other mental health conditions
How to use "paroxetine hydrochloride" in a sentence
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paroxetine hydrochloride
The structure of paroxetine hydrochloride is presented below.
The current formulation which is the only marketed formulation of paroxetine hydrochloride is a swallow tablet.
Amorphous paroxetine hydrochloride and method of producing it.
Method of producing amorphous paroxetine hydrochloride.
Paroxetine hydrochloride exists in amorphous as well as crystalline forms.
It is possible to produce amorphous paroxetine hydrochloride which is useful as a medicine.
FTIR analysis results were wholly consistent with PVP and paroxetine hydrochloride.
The crystals of paroxetine hydrochloride anhydrate containing isopropyl alcohol are extremely thermally unstable.
Use according to claim I in which paroxetine is used as paroxetine hydrochloride.
We have found that amorphous paroxetine hydrochloride is a hygroscopic solid of poor handling qualities.
TECHNICAL FIELD The present invention relates to a process for drying paroxetine hydrochloride anhydrate.
The amorphous paroxetine hydrochloride of the present invention is a powder which substantially contains no crystals.
The invention further provides a formulation of paroxetine hydrochloride for use in the treatment of depression.
BACKGROUND ART Paroxetine hydrochlorides such as paroxetine hydrochloride anhydrate are useful compounds as antidepressants.
Advantageously the product is the Form A anhydrate of paroxetine hydrochloride.
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A process for drying paroxetine hydrochloride anhydrate comprising,.
Treating with a hydrochloric acid de-formylation agent results in the formation of paroxetine hydrochloride.
A preferred salt is crystalline paroxetine hydrochloride hemi-hydrate.
Desolvated paroxetine hydrochloride solvate obtainable by a process as claimed in any one of claims 1 to 5.
The structural formula of paroxetine hydrochloride is,.
Crystalline paroxetine hydrochloride acetone propan-2-ol mixed solvate.
As a result, the crystals were found to be paroxetine hydrochloride hemihydrate.
Moreover, crystalline paroxetine hydrochloride hemihydrate exhibits only limited solubility in water.
The infra-red spectrum obtained was consistent with that of crystalline paroxetine hydrochloride hemihydrate.
In the crystals of the resulting paroxetine hydrochloride anhydrate, isopropyl alcohol is contained.
During the treatment with the transformation solvent, a proportion of the paroxetine hydrochloride may dissolve.
However, the preparation of paroxetine hydrochloride has not been described in the literature.
The infra-red spectrum obtained was consistent with that obtained for crystalline paroxetine hydrochloride hemihydrate.
Controlled Substance Class, Paroxetine hydrochloride is not a controlled substance.
Figure 1 is the X-ray powder diffraction pattern of the amorphous paroxetine hydrochloride.
A process for the production of paroxetine hydrochloride anhydrate comprising,.
Paroxetine hydrochloride was thus precipitated, filtered, washed and dried.
Use according to claim 2 in which paroxetine hydrochloride is used as the hemihydrate.
Paroxetine hydrochloride ( Paxil ) is widely used as an antidepressant.
In a preferred aspect, this invention provides paroxetine hydrochloride hemihydrate which is substantially pure.
Crystalline paroxetine hydrochloride which is solvated with propan-2-ol and at least one other solvent.
Among them, venlafaxine hydrochloride, fluoxetine hydrochloride, paroxetine hydrochloride and paroxetine hydrochloride hydrate are preferred.
This paroxetine hydrochloride anhydrate usually contains 30 to 70 % by weight or so of isopropyl alcohol.
Examples of paroxetine compositions include a paroxetine hydrochloride tablet, tablet core, and tabletting composition.
Preferably the propan-2-ol is anhydrous to suppress formation of paroxetine hydrochloride hemihydrate.
The resulting crystals of the paroxetine hydrochloride anhydrate contained 53.5 % by weight of isopropyl alcohol.
Especially the present invention provides crystalline paroxetine hydrochloride acetone propan-2-ol mixed solvate.
EP 223403 discloses paroxetine hydrochloride hemihydrate and pharmaceutical compositions based thereon.
Each controlled-release tablet contains paroxetine hydrochloride equivalent to 12.5 mg paroxetine.
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Examples of using Paroxetine
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Certain drugs for depression such as paroxetine
Known hypersensitivity to paroxetine or any of the excipients
Examples of using Hydrochloride
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Metformin hydrochloride is excreted unchanged in the urine
Precipitation of the imidazole hydrochloride started immediately
Ambroxol hydrochloride is secreted into breast milk
